Journal of Capital Medical University ›› 2017, Vol. 38 ›› Issue (3): 451-456.doi: 10.3969/j.issn.1006-7795.2017.03.023

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Clinical application of concentrate growth factors combined with bone substitute in site preservation of maxillary anterior region

Lin Shichen1, Duan Shaoyu1, Zhu Jing2, Song Wanhong1, Yang Lian1, Sun Dandan1   

  1. 1. Department of Stomatology, Beijing Electric Power Hospital, Capital Medical University, Beijing 100073, China;
    2. Department of Stomatology, Outpatient Department of Xinhua News Agency, Beijing 100031, China
  • Received:2017-03-30 Online:2017-05-21 Published:2017-06-14
  • Supported by:
    This study was supported by Science and Technology Project of State Grid Corporation of China(SGHB000AJJS1400182).

Abstract: Objective To evaluate the clinical effect of site preservation by using concentrate growth factors (CGF) combined with Bio-oss bone powder in maxillary anterior region. Methods Thirty-two maxillary anterior teeth of 26 patients that should be extracted were randomly divided into two groups. For CGF group(16 cases), CGF combined with Bio-oss was implanted into teeth extraction socket, then covered the socket with CGF membrane; for control group(16 cases), teeth extraction socket was placed with hemostatic sponge after scoraping. Cone beam computed tomography (CBCT) should be taken after 6 months, then compared with preoperative, observed and measured the change of width and height of the alveolar bone at extraction site. Results In CGF group, the heights of labial and palatal bone plates between 6 months after surgery and preoperative were no statistically significant (P>0.05), and the widths between 6 months after surgery and preoperative were statistically significant (P<0.05). In control group, the heights of labial and palatal bone plates and the widths between 6 months after surgery and preoperative were statistically significant (P<0.05). The differences of changes between the two groups were statistically significant (P<0.05). Conclusion CGF combined with Bio-oss being used for preservation of teeth extraction site, which may effectively keep the width and height of alveolar ridge, it is favorable for implanting and repairing.

Key words: site preservation, concentrate growth factors(CGF), Bio-oss, cone beam computed tomography(CBCT)

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