Correlation between coagulation and progressive hemorrhagic injury in elderly patients with acute traumatic brain injury

doi:10.3969/j.issn.1006-7795.2020.02.028

Abstract

Abstract: Traumatic brain injury (TBI) refers to the brain injury caused by external force, As which is the disease with the highest fatality rate and disability rate in the whole body trauma. As one of its serious complications, progressive hemorrhagic injury(PHI) is the main cause of death in patients with craniocerebral trauma,and coagulation dysfunction is one of its main pathophysiological mechanisms. The proportion of elderly patients with craniocerebral trauma gradually increases with the aging of the population. Meanwhile, age is a risk factor for progressive hemorrhagic injury. Elderly patients with craniocerebral trauma are prone to suffering from progressive hemorrhagic injury,with worse state and prognosis than those of non-elderly patients once PHI occurs. Therefore, exploration of the correlation between coagulation indexes and progressive hemorrhagic injury in elderly patients with TBI and the predictive value of each coagulation index to PHI is conducive to clinical reference for early detection and timely diagnosis and treatment. In this paper, we reviewed the research progresses of coagulation disorder and progressive hemorrhagic brain injury after traumatic brain injury in the elderly.

Key words: traumatic brain injury(TBI), progressive hemorrhagic injury(PHI), coagulation, the elderly

CLC Number:

R651

Hu Yue, Song Haozhe, Chen Jiashu, Liang Yuting, Zhao Anqi, Wang Murong, Li Lizhuo. Correlation between coagulation and progressive hemorrhagic injury in elderly patients with acute traumatic brain injury[J]. Journal of Capital Medical University, 2020, 41(2): 302-306.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2020.02.028

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2020/V41/I2/302

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