Reproductive outcomes of women treated for intrauterine adhesions following uterine artery embolization

doi:10.3969/j.issn.1006-7795.2022.03.025

Abstract

Abstract: Objective To assess the reproductive outcomes of women treated for intrauterine adhesions (IUA) following uterine artery embolization (UAE). Methods Retrospective study of 129 women with IUA following UAE wishing to conceive, undergoing hysteroscopic adhesiolysis at a tertiary Hysteroscopic Centre of Futting Hospital. The main outcome measures included the American Fertility Society (AFS) IUA score of pre-and post-operation, improvement in menstrual flow and reproductive outcomes. Results Complete follow-up was available for 124 women. Following hysteroscopic adhesiolysis, there was a significant reduction in the AFS score [10 (8,10) vs 4 (4,6)], P<0.05), while 62/124 (50%) of patients experienced an improvement in menstrual flow. Of 124 women wishing to conceive, 29/124 (23.4%) achieved a pregnancy and 22/124 (17.7%) achieved a live birth. Of the 29 pregnant women, 6/29 (20.7%) miscarried, 9/29 (31.0%) had a preterm labour, 13/29 (44.8%) had a term live birth and 1/29 (3.4%) has an ongoing pregnancy. Among those achieving a live birth, 90.9% (20/22) suffered significant obstetric complications including abnormal placental implantation 16/22 (72.7%), significant post-partum haemorrhage 12/22 (54.5%), transfusing 5/22 (22.7%), need for further UAE 3/22 (13.6%) and caesarean hysterectomy 1/22 (4.5%). Conclusion It appears that approximately one-sixth women treated for IUA following UAE will achieve a live birth, of which the majority will suffer significant obstetric complications.

Key words: intrauterine adhesions, hysteroscopy, uterine artery embolization, reproductive prognosis

CLC Number:

R711.75

Zhou Qiaoyun, Huang Xiaowu, Xia Enlan, Zhao Yuting, Huang Rui. Reproductive outcomes of women treated for intrauterine adhesions following uterine artery embolization[J]. Journal of Capital Medical University, 2022, 43(3): 490-494.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2022.03.025

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2022/V43/I3/490

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