Journal of Capital Medical University ›› 2019, Vol. 40 ›› Issue (4): 549-553.doi: 10.3969/j.issn.1006-7795.2019.04.011

• Gynecological Endocrinology and Menopause • Previous Articles     Next Articles

Clinical application of mini-hysteroscopy in infertility patients

Ruan Xiangyan1,2, Zhang Luping1, Dai Yinmei1, Wang Husheng1, Jin Fengyu1, Gu Muqing1, Cheng Jiaojiao1, Ju Rui1, Min Min1   

  1. 1. Department of Endocrinology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China;
    2. Department for Women's Health, University Women's Hospital and Research Center for Women's Health, University of Tuebingen, Tuebingen D-72076, Germany;
    3. Women's Hospital Cologne-Weyerthal, University of Cologne, Cologne D-50931, Germany
  • Received:2019-05-20 Online:2019-07-21 Published:2019-07-19
  • Supported by:
    This study was supported by Beijing Municipal Administration of Hospitals'Ascent Plan(DFL20181401),Natural Science Foundation of Beijing(7162062), Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support(XMLX201710).

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Abstract: Objective To investigate the clinical application of mini hysteroscopy in infertility patients. Methods From Sep 2017 to Jan 2019, 159 cases of infertility patients were enrolled, who have accepted mini-hysteroscopy examination in the Department of Gynecological Endocrinology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University. The patients who had primary ovary insufficiency, tubal infertility were excluded, patients with hysteroscopy contradiction, such as acute or sub-acute vaginal tract inflammation, endometrium lesion or endometrium carcinoma, severe cardiovascular, liver or kidney insufficiency were excluded. Twelve patients lost follow. 110 patients were eventually included in the analysis. The patient's age, body mass index (BMI), infertility etiology, preoperative and postoperative stimulate ovulation cycle, pregnancy state and pregnancy time were recorded. The effect of outpatient mini-hysteroscopy on ovulation induction cycle was analyzed in pregnant patients.Results The average age of 110 patients was 31.95±4.86 years old. 77 (70%) patients were found to have intrauterine abnormalities, while 33 (30%) patients were found to have normal intrauterine cavity. 37 cases of pregnancy, accounting for 33.63%. The median of ovulation induction cycles before and after surgery were respectively 3 (0-15)and 1 (0-3), with statistically significant differences between the two groups(P<0.05). Among the 37 pregnant patients, 21 of them had no structural lesions in hysteroscopy. The ovulation induction cycle of these patients before and after hysteroscopy were respectively 5 (0-9) and 1 (0-3), with statistically significant differences between the two groups(P0.05). Conclusion Outpatient mini-hysteroscopy can not only timely detect the intrauterine abnormalities but also provide accurate diagnosis and treatment program, suggesting a great application value for the diagnosis of uterine factors and shorten the ovulation cycle in infertility patients. In polycystic ovarian syndrome (PCOS) patients, the pregnancy rate significantly increased in the short term after mini-hysteroscopy, and the mechanism remains to be explored.

Key words: mini-hysteroscopy, infertility, polycystic ovarian syndrome(PCOS), endometrium scratch

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