Abstract:

Objective To evaluate the effect of oral administration of Yunnan Baiyao on the reduction of postoperative pain, swelling and trismus after the extraction of the mandibular impacted third molar.
Methods According to the completely random double-blind design, 48 enrolled patients were divided into experimental and control groups equally. Patients were orally administered with Yunnan Baiyao capsules or placebo capsules for 8 days, starting from 3 days before the operation. Three-dimensional facial scans of patients were performed in the preoperative and postoperative first day, third and fifth day respectively, and the facial three-dimensional images were reconstructed. Using reverse engineering software, the facial swelling degree, pain intensity and trismus in different time points were quantified and analyzed.
Results There were no statistical significance in trismus，pain intensity and swollen volume between the two groups. The facial swelling thickness and swelling degree had significant statistical differences between the two groups.
Conclusion Oral administration of Yunnan Baiyao capsules in the perioperative period can prevent and reduce the facial swelling after the extraction of the mandibular impacted third molar.

Key words: Yunnan Baiyao, mandibular impacted third molar, facial swelling, three-dimensional face image reconstruction