Abstract: Gene chip technology has successfully been used in the investigation of a diverse array of heart disease as well as other human diseases. It has been used in gene sequence, gene mutation, functional analyses, screening assay, new medicine development and detection of pathogens since 1990. Gene chip technology has been used in cardiovascular disease since 1999. But by now, it has been not used commonly in cardiovascular surgery research.Summarizing the application of gene chip in experimental research of cardiovascular surgery in this paper. Assessing its values and reviewing research progress of cardiovascular surgery. The main ideas of these articles were summarized and analyzed. The successful application of gene chip in the area of cardiovascular surgery revealed lots of unknown things. Gene chip should be used in the area of cardiovascular surgery more and more. It may provide clues and point out directions for the area.

Key words: gene chip, heart diseases