Abstract: Objective To explore the relationship between atherosclerotic heart disease and cerebrovascular disease through cardiac and cerebral angiography, to analyze the distribution characteristics of intracranial and extracranial sections lesions of upper-aortic arteries in patients with coronary artery disease (CAD). Methods According to the result of the coronary angiography (CAG),180 patients who were suspected to have coronary heart disease were divided into non-CAD group and CAD group. Cerebral angiography was performed in all patients, and all patients also provided information about physical history,age,sex,body mass index(BMI),smoking,and the results of blood routine tests,glycosylated hemoglobin,coagulation function,high sensitivity C-reactive protein(hs-CRP), homocysteine(HCY) and biochemical test were analyzed and the relationship between the lesions of coronary artery lesions and intracranial, extracranial sections of upper-aortic artery was explored,and the correlation of the two groups of subjects was analyzed with logistic regression model. Results There was no significant difference between CAD and non-CAD group in the intracranial carotid, extracranial carotid and intracranial vertebra(P=0.166,0.146,0.128). The incidence of extracranial vertebral artery stenosis in CAD group were significantly higher than that of non-CAD group(P=0.010).Conclusion Coronary artery lesions may be closely related to extracranial vertebral artery lesions.

Key words: coronary artery disease, coronary angiography, cerebral artery angiography, cerebral artery stenosis