Risk factors and pathogenic bacteria of catheter-related blood stream infection in ICU

doi:10.3969/j.issn.1006-7795.2020.01.024

Abstract

Abstract: Objective To understand the infection rate, risk factors, pathogen species, drug resistance and prognosis of catheter-related blood stream infection (CRBSI) in the Intensive Care Unit (ICU) of Peking University International Hospital, and to provide guidance for reducing the incidence of CRBSI. Methods Clinical and microbiological data of patients diagnosed with CRBSI from January 1, 2016 to December 31, 2018 in the Intensive Care Unit of Peking University International Hospital were retrospectively analyzed. Results This study involved in 674 cases of central venous catheter indwelling, 6 197 days of catheterization, and 28 cases of CRBSI, with an infection rate of 4.52‰. A total of 36 strains of pathogenic bacteria were cultured in 28 patients, including 18 Gram-positive strains (50%).There were 16 Gram-negative bacteria (44.4%) and 2 fungi (5.6%). Staphylococcus epidermidis dominated by G+ bacteria, acinetobacter baumannii dominated by G-bacteria, and candida albicans dominated by fungi. Logistic multiple regression analysis showed that heavy antibiotic use and indwelling catheter duration were independent risk factors for CRBSI in the ICU. Conclusion The incidence of CRBSI in ICU is still high, and the pathogen is mainly G+ bacteria.

Key words: catheter-related bloodstream infection, Intensive Care Unit(ICU), pathogenic bacteria

CLC Number:

R446.5

Qiao Li, Cao Yang, Yuan Hongxun, Wang Yao. Risk factors and pathogenic bacteria of catheter-related blood stream infection in ICU[J]. Journal of Capital Medical University, 2020, 41(1): 125-130.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2020.01.024

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2020/V41/I1/125

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