New progresses in ovarian tissue cryopreservation and transplantation

doi:10.3969/j.issn.1006-7795.2024.04.011

Abstract

Abstract: Ovarian tissue cryopreservation and transplantation not only protect female fertility but also preserve ovarian endocrine function. It is effective in the prevention and treatment of iatrogenic premature ovarian insufficiency, especially in prepubertal girls and women in urgent need of disease treatment. The efficacy and safety of ovarian tissue cryopreservation have proved, and the current clinical gold standard is slow freezing, while vitrification is only for research. Despite the rapid development of this technique in recent years, it still faces problems such as cryoinjury, toxicity of cryoprotectants, assessment of follicular reserve, and safety of cryopreservation and transplantation. This article summarizes the progresses of research on these issues.

Key words: ovarian tissue cryopreservation and transplantation, cryoinjury, follicular reserve, safety

CLC Number:

R711

Du Juan, Ruan Xiangyan. New progresses in ovarian tissue cryopreservation and transplantation[J]. Journal of Capital Medical University, 2024, 45(4): 629-635.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2024.04.011

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2024/V45/I4/629

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