Advances in clinical application and perioperative studies of glucagon-like peptide-1 receptor agonists

doi:10.3969/j.issn.1006-7795.2024.06.024

Abstract

Abstract: Glucagon-like peptide-1 receptor agonists (GLP-1RA) have an important therapeutic role in controlling blood glucose levels in patients with type 2 diabetes mellitus (T2DM) and reducing body weight in obese patients. Recent studies have showed that by acting on GLP-1R distributed throughout the body, the drug may also have some effect on other important systems of the body, such as reducing the incidence of cardiovascular events, delaying the progression of chronic kidney disease, and increasing the risk of adverse events in the digestive system. As the use of this drug increase in the population, the potential for patients to experience an increase in perioperative adverse events such as delayed gastric emptying and the occurrence of reflux aspiration needs to be emphasized. This article summarizes the pharmacological characteristics of these drugs and their perioperative studies as follows.

Key words: glucagon-like peptide-1 receptor agonists, perioperative period, type 2 diabetes mellitus, diet pills

CLC Number:

R969.3

Wang Tianyuan, Yu Yun, Han Ruquan. Advances in clinical application and perioperative studies of glucagon-like peptide-1 receptor agonists[J]. Journal of Capital Medical University, 2024, 45(6): 1115-1121.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2024.06.024

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2024/V45/I6/1115

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