肠道微生态与银屑病的中医研究

doi:10.3969/j.issn.1006-7795.2019.03.008

首都医科大学学报 ›› 2019, Vol. 40 ›› Issue (3): 363-368.doi: 10.3969/j.issn.1006-7795.2019.03.008

肠道微生态与银屑病的中医研究

刘欣¹, 张广中², 姜春燕², 肖士菊², 谭勇³, 曲剑华², 陈妍霏¹

1. 北京中医药大学研究生院, 北京 100029;
2. 首都医科大学附属北京中医医院皮肤科, 北京 100010;
3. 中国中医科学院中医临床基础医学研究所, 北京 100700

收稿日期:2019-03-15 出版日期:2019-05-21 发布日期:2019-06-13
通讯作者: 姜春燕 E-mail:tcmjcy@126.com
基金资助:
国家自然科学基金（81273766，8167397），北京市自然科学基金（7172097），北京市属医院科研培育计划项目（PZ2019024）。

The traditional Chinese medicine in the treatment of gut microbiota and psoriasis

Liu Xin¹, Zhang Guangzhong², Jiang Chunyan², Xiao Shiju², Tan Yong³, Qu Jianhua², Chen Yanfei¹

1. Graduate School of Beijing University of Traditional Chinese Medicine, Beijing 100029, China;
2. Department of Dermatology, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, China;
3. Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China

Received:2019-03-15 Online:2019-05-21 Published:2019-06-13
Supported by:
This study was supported by National Natural Science Foundation of China (81273766,8167397),Natural Science Foundation of Beijing (7172097),Scientific Research and Cultivation Program of Beijing Subordinate Hospital (PZ2019024).

摘要/Abstract

摘要： 银屑病是一种常见的以慢性炎性反应为特征的全身心身疾病，与肠道菌群紊乱密切相关。中医的整体观和恒动观与肠道微生态的整体性、动态性特征相契合；"肺与大肠相表里"、"肺主皮毛"、"肠-脑-皮轴"学说，及已有有关中医药维持肠道微生态稳态的研究，为从肠道微生态角度探索银屑病的中医诊治机制提供了依据。将传统中医证候与客观的微生态学相结合，明确不同中医证型肠道微生态的特征性变化，探究可调节此类肠道微生态失调的中药复方制剂或单味药物，通过肠道菌群与中医"方"和"证"结合研究以寻找中医药治疗银屑病的新思路及新方法。

关键词: 银屑病, 肠道微生态, 中医研究

Abstract: Psoriasis is a common systemic psychosomatic disorder characterized with immune-mediated chronic relapsing-remitting inflammation, which is closely related to intestinal flora dermatosis. The integrity and dynamic characteristics of the intestinal micro-ecology are consistent with the holistic view and perpetual motion view in traditional Chinese medicine (TCM). Some theories such as "The lung and the large intestine are interior-exteriorly related", "Lung relating to skin theory" and "Gut-brain-skin axis theory", and some researches on TCM maintaining the balance of intestinal microecology, provide a basis for exploring the TCM mechanism of diagnosis and treatment of psoriasis from the perspective of intestinal microecology. Based on a review of modern medical research on intestinal flora disorders and psoriasis vulgaris, this article interpreted the theories of TCM researches on intestinal flora of psoriasis, and explored the regulation function of intestinal microflora in TCM prevention and treatment of psoriasis. The new thought of TCM treating psoriasis by regulating intestinal microecology was proposed.

Key words: psoriasis, gut microbiota, traditional Chinese medicine research

中图分类号:

R275.1

刘欣, 张广中, 姜春燕, 肖士菊, 谭勇, 曲剑华, 陈妍霏. 肠道微生态与银屑病的中医研究[J]. 首都医科大学学报, 2019, 40(3): 363-368.

Liu Xin, Zhang Guangzhong, Jiang Chunyan, Xiao Shiju, Tan Yong, Qu Jianhua, Chen Yanfei. The traditional Chinese medicine in the treatment of gut microbiota and psoriasis[J]. Journal of Capital Medical University, 2019, 40(3): 363-368.

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肠道微生态与银屑病的中医研究

The traditional Chinese medicine in the treatment of gut microbiota and psoriasis

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