关键词: 神经外科儿童, 谵妄和躁动, 麻醉苏醒期, 危险因素

Abstract: Objective  To explore the risk factors of delirium and agitation in pediatric neurosurgery patients during anesthesia emergency. Methods  The clinical data of pediatric neurosurgery patients were retrospectively investigated with 120 cases  in the delirium and agitation group, and 392 cases  in the matched control group. Multivariate Logistic regression analysis was used to explore the risk factors of delirium and agitation in pediatric neurosurgery patients during anesthesia emergency. Results  Multivariate Logistic regression analysis showed that oral midazolam before operation (OR=2.695, 95% CI： 1.183－6.139, P=0.018), intraoperative infusion of dexmedetomidine (OR=0.210, 95% CI： 0.049－0.902, P=0.036) and combined inhalation anesthesia (OR=2.862, 95% CI： 1.300－6.301, P=0.009) were the risk factors of delirium and agitation in pediatric neurosurgery patients during anesthesia emergency. Conclusion  Oral midazolam before entering the operating room and combined inhalation anesthesia are independent risk factors for delirium and agitation, and dexmedetomidine can reduce the occurrence of delirium and agitation for pediatric neurosurgery patients.

Key words: pediatric neurosurgery patients, delirium and agitation, anesthesia emergency, risk factors