首都医科大学学报 ›› 2023, Vol. 44 ›› Issue (2): 244-247.doi: 10.3969/j.issn.1006-7795.2023.02.010

• 麻醉神经科学 • 上一篇    下一篇

儿童神经外科麻醉苏醒期谵妄和躁动的危险因素分析

王成尉*,袁琳淞,周扬,王会文   

  1. 首都医科大学附属北京天坛医院麻醉科, 北京 100050
  • 收稿日期:2023-02-01 出版日期:2023-04-21 发布日期:2023-04-18
  • 通讯作者: 王成尉 E-mail:13501111323@126.com
  • 基金资助:
    北京市科委科技计划项目(Z19110700660000)

Analysis of risk factors of delirium and agitation during anesthesia emergence in pediatric neurosurgery patients

Wang Chengwei*, Yuan Linsong, Zhou Yang,Wang Huiwen   

  1. Department of Anaesthesiology,Beijing Tiantan Hospital,Capital Medical University, Beijing 100050, China
  • Received:2023-02-01 Online:2023-04-21 Published:2023-04-18
  • Supported by:
    This study was supported by Science and Technology Program of Beijing Municipal Commission of Science and Technology(Z19110700660000)

摘要: 目的  探讨神经外科患儿麻醉苏醒期谵妄和躁动的影响因素。方法  回顾性调查512例神经外科手术患儿的临床资料,其中苏醒期谵妄躁动组120例,经匹配对照组392例。采用多因素Logistic回归分析检验神经外科患儿麻醉苏醒期发生谵妄和躁动的影响因素。 结果  多因素Logistic回归分析显示,术前口服咪达唑仑(OR=2.695,95%CI: 1.183~6.139,P =0.018)、术中应用右美托咪定(OR=0.210,95%CI: 0.049~0.902,P=0.036)和复合吸入麻醉(OR=2.862,95%CI: 1.300~6.301,P=0.009)是神经外科患儿麻醉恢复期发生谵妄和躁动的影响因素。 结论  入手术室前口服咪达唑仑、复合吸入麻醉方法是发生谵妄和躁动的独立危险因素,麻醉维持应用右美托咪定可降低谵妄和躁动发生。

关键词: 神经外科儿童, 谵妄和躁动, 麻醉苏醒期, 危险因素

Abstract: Objective  To explore the risk factors of delirium and agitation in pediatric neurosurgery patients during anesthesia emergency. Methods  The clinical data of pediatric neurosurgery patients were retrospectively investigated with 120 cases  in the delirium and agitation group, and 392 cases  in the matched control group. Multivariate Logistic regression analysis was used to explore the risk factors of delirium and agitation in pediatric neurosurgery patients during anesthesia emergency. Results  Multivariate Logistic regression analysis showed that oral midazolam before operation (OR=2.695, 95% CI: 1.183-6.139, P=0.018), intraoperative infusion of dexmedetomidine (OR=0.210, 95% CI: 0.049-0.902, P=0.036) and combined inhalation anesthesia (OR=2.862, 95% CI: 1.300-6.301, P=0.009) were the risk factors of delirium and agitation in pediatric neurosurgery patients during anesthesia emergency. Conclusion  Oral midazolam before entering the operating room and combined inhalation anesthesia are independent risk factors for delirium and agitation, and dexmedetomidine can reduce the occurrence of delirium and agitation for pediatric neurosurgery patients.

Key words: pediatric neurosurgery patients, delirium and agitation, anesthesia emergency, risk factors

中图分类号: