首都医科大学学报 ›› 1994, Vol. 15 ›› Issue (4): 254-256.

• 论著 • 上一篇    下一篇

银杏叶提取物对小鼠淋巴细胞和中性粒细胞活性的影响

沈海中1, 张力平1, 赵文明1, 夏楠2   

  1. 1. 首都医学院微生物学教研室;2. 北京市理化分析测试中心
  • 收稿日期:1993-09-03 修回日期:1900-01-01 出版日期:1994-10-15 发布日期:1994-10-15

Effects of the Extracts from the Leaves of Ginkgo Biloba on the Activity of Murine Lymphocytes and Neutrophils

Shen Haizhong1, Zhang Liping1, Zhao Wenming1, Xia Nan2   

  1. 1. Department of Microbiology, Capital Institute of Medicine;2. Beijing Center of Physical & Chemical Analysis
  • Received:1993-09-03 Revised:1900-01-01 Online:1994-10-15 Published:1994-10-15

摘要: 用噻唑蓝[3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide,MTT]比色法和髓过氧化物酶(myeloperoxidase,MPO)微量测定法分别检测了银杏叶3种提取物对小鼠淋巴细胞活性和中性粒细胞吞噬杀伤功能的影响.结果显示,银杏叶提取物可明显增强小鼠淋巴细胞线粒体脱氢酶(P<0.001)和中性粒细胞MPO的释放(P<0.01~0.001).由此可见,银杏叶提取物具有提高小鼠机体免疫细胞功能的作用.

关键词: 银杏叶提取物, 淋巴细胞, 中性粒细胞, MPO微量测定法

Abstract: The effects of extracts from the leaves of Ginkgo biloba on the activity of murine lymphocytes and neutrophils were investigated by colorimetric 3-(4,5-dimethylthiazol-2-y)-2, 5-diphenyltetrazolium bromide(MTT)assay and micromeasurement of myeloperoxidase(MPO). The results show that the activity of plastiosome dehydrogenase in lymphocytes(P<0.001)and the MPO release of neutrophils(P<0.01)were enhanced when the cells were pretreated with the extracts from the leaves of Ginkgo biloba. Together these findings indicate these extracts may strengthen the function of murine immunocytes.

Key words: extracts from the leaves of Ginkgo biloba, lymphocyte, neutrophil, micromeasurement of MPO

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