首都医科大学学报 ›› 2006, Vol. 27 ›› Issue (6): 758-760.

• 专题报道 • 上一篇    下一篇

梅毒合并HIV感染6例报告

高艳青, 黄晓婕, 吴昊, 张彤, 郭彩萍, 梁连春   

  1. 首都医科大学附属北京佑安医院性病艾滋病临床诊疗中心
  • 收稿日期:2006-09-26 修回日期:1900-01-01 出版日期:2006-12-24 发布日期:2006-12-24

Coincident Infections of Syphilis with HIV

Gao Yanqing, Huang Xiaojie, Wu Hao, Zhang Tong, Guo Caiping, Liang Lianchun   

  1. Clinical Center of STDS and AIDS, Beijing Youan Hospital, Capital University of Medical Sciences
  • Received:2006-09-26 Revised:1900-01-01 Online:2006-12-24 Published:2006-12-24

摘要: 目的 探讨梅毒合并HIV感染的临床表现及转归.方法 对北京佑安医院感染科收治的6例梅毒合并HIV感染者的性别、好发人群、临床表现、实验室检查、诊断方法、治疗经过及转归进行回顾性分析.结果 6例梅毒合并HIV感染的患者均为男性同性恋者,其中3例脑脊液有异常改变,所有患者对青霉素治疗均反应良好.结论 男性同性恋人群是梅毒和HIV共感染的高危人群,临床表现多样,可以迅速进展到神经梅毒.主要依靠梅毒血清学试验和全面细致的查体进行诊断.青霉素为首选治疗药物,治疗后的密切随访至关重要.

关键词: 梅毒, 人类免疫缺陷病毒, 共感染, 神经梅毒

Abstract: Objective To investigate the manisfetations of coincident infection syphilis with HIV.Methods Patients diagnosed as having HIV and syphilis coinfection in Beijing Youan Hospital were retrospecpectively studied.Their demorgraphic data,clinical manisfetations,diagnostic means,treatment and follow-up results were analyzed.Results 6 patients with syphilis and HIV coinfection were all homosexual men,among them three cases had abnormal CSF,all patients responded well to penicillin.Conclusion There is a high incidence of HIV and syphilis coinfection in homosexual men.Syphilis may present with atypical features in the HIV-positive patients,serious courses with rapid progression and CNS involvement are observed more frequently.Diagnosis is generally made with serology,but the clinician should be aware of the potential for false-negative serology.All HIV-positive patients should be treated with a penicillin-based regimen.All HIV-positive patients should be considered for the evaluation of neurosyphilis.Relapse is a real concern and careful follow up is required.

Key words: syphilis, HIV, coinfection, neurosyphilis

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