首都医科大学学报 ›› 2023, Vol. 44 ›› Issue (2): 179-185.doi: 10.3969/j.issn.1006-7795.2023.02.001

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现代免疫学在感染性疾病、过敏性疾病、肿瘤和神经系统疾病中的研究进展

陈彦,张须龙,许江南,贾玉峰,孙英*   

  1. 首都医科大学基础医学院免疫学系,北京  100069
  • 收稿日期:2023-01-24 出版日期:2023-04-21 发布日期:2023-04-17
  • 通讯作者: 孙英 E-mail:ying.sun@ccmu.edu.cn
  • 基金资助:
    北京市属高校高水平教师队伍建设支持计划高水平创新团队建设计划项目(IDHT20190510)

Advances in modern immunology in infectious diseases, allergic diseases, tumors, and neurological disorders

Chen Yan,  Zhang Xulong,  Xu Jiangnan,  Jia Yufeng, Sun Ying*   

  1. Department of Immunology, School of Basic Medical Sciences, Capital Medical University, Beijing 100069, China
  • Received:2023-01-24 Online:2023-04-21 Published:2023-04-17
  • Supported by:

    This study was supported by  High-level Teachers in Beijing Municipal Universities in the Period of 13th Five-year Plan(IDHT20190510)


摘要:

免疫学(immunology)作为一门交叉学科,其研究内容涉及多种学科和不同疾病的诸多方面。近年来,免疫学在基础和临床研究方面取得诸多突破性进展,并深化了对众多常见疾病中的免疫应答及调控机制的认识,为揭示免疫相关疾病的发病机制提供了新的科学依据和临床防治手段。本文对研究较为深入的免疫学中关键的细胞和重要信号通路以及细胞因子等在感染性疾病、过敏性疾病、肿瘤和神经系统疾病这四个方面的进展概况加以概述。

关键词: 感染性疾病, 过敏性疾病, 肿瘤, 神经系统疾病, 免疫

Abstract:

Immunology, as an interdisciplinary subject, involves a variety of subjects and many aspects of different diseases. For the past few years, many breakthroughs have been made in basic and clinical research of immunology, which has deepened the understanding of immunological response and its regulatory mechanism in many common diseases. These findings provide a new scientific basis and clinical means of prevention and treatment for the pathogenesis of immune-related diseases. In this review, we  focus on the key cells and important signaling pathways in immunology, and the role of cytokines in infectious diseases, allergic diseases, tumors and neurological disorders.

Key words: infectious diseases, allergic diseases, tumor, neurological diseases, immunity

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