Abstract: Objective To analyze the changes of intraocular pressure and anterior chamber angle after intravitreal silicone oil injection. Methods Retrospective analysis of intraocular pressure(IOP) was performed in 27 patients(29 eyes) after intravitreal silicone oil injection. Before the silicone oil was removed, all the eyes were examined by ultrasound biomicroscopy(UBM), slit-lamp microscope and non-contact tonometer. After the silicone oil was removed, all the eyes were examined by non-contact tonometer. Results Twelve eyes were diagnosed as silicone oil glaucoma(SOG). The incidence of SOG was 41.4%. Ocular hypertension began from the second day to 4 years after the operation during which silicone oil was injected. By ultrasound biomicroscopy and slit-lamp, It was found that there was more silicone oil in the anterior chamber, emulsified silicone oil, peripheral anterior synechia of iris, intraocular lens and aphacia in glaucoma eyes as compared with normal IOP eyes. After silicone oil removal, the IOP of most of silicone oil glaucoma eyes became normal. Conclusion Silicone oil in anterior chamber, emulsified silicone oil, peripheral anterior synechia of iris, intraocular lens and aphacia were the main causes of silicone oil glaucoma. Removing silicone oil was effective in treatment of silicone oil glaucoma.

Key words: silicone oil, intraocular pressure, ultrasound biomicroscopy