Journal of Capital Medical University ›› 2014, Vol. 35 ›› Issue (1): 6-9.doi: 10.3969/j.issn.1006-7795.2014.01.002

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This study was awarded with The Second Grade National Prize for Science and Technology Progress—Pathogenesis and treatment strategy of primary angle closure glaucoma

Wang Huaizhou, Wang Ningli   

  1. Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China
  • Received:2014-01-16 Online:2014-02-21 Published:2014-02-21

Abstract:

Primary angle closure glaucoma(PACG) is the most prevalent and irreversible blindness disease in China and Asia and the blindness rate is as high as 37.5%~75.0%. We systemically investigated the structure of the anterior chamber angle and for the first time found the mechanism of angle closure of PACG. Then we established the new PACG classification system. We also launched a genetic research in Asia with 8 countries and areas and found 4 susceptibility genes which were related with the anatomical structure of the anterior chamber angle. We designed and developed the first panoramic ultrasound biomicroscopy (UBM) and early screening method and intervention technology. We found the new molecular mechanism of acute PACG and designed treatment route of acute PACG. We established a step by step treatment mode with drug, laser and surgery of PACG and improved the surgery technique. In a word,the serial study promoted recognition,diagnosis,and treatment of PACG. By the item we completed our nation's PACG prevention and treatment made a leap from following others to leading the area.

Key words: primary angle closure glaucoma, mechanism, screening, diagnosis, treatment

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