Clinical significance of joint detection of serum homocysteine, lipoprotein(a) and high sensitive C-reactive protein in cerebral infarction

doi:10.3969/j.issn.1006-7795.2015.05.023

Abstract

Abstract: Objective To investigate the changes and the clinical significance of joint detection of serum homocysteine (HCY), lipoprotein(a)[Lp(a)] and high sensitive C-reactive protein (hs-CRP) in patients with cerebral infarction. The cut of value of three results of the patients with cerebral infarction was determined by ROC curve. Methods The levels of HCY, Lp(a),hs-CRP were measured in 183 patients with cerebral infarction and 163 healthy controls and the results were made statistical analysis. Results The levels of Hcy,Lp(a) and hs-CRP in patients with cerebral infarction were (16.7±6.3) μmol/L, (343.6±150.1)mg/L, (3.87±1.88)mg/L, in healthy control group were (12.9±4.7) μmol/L, (205.4±190)mg/L,(2.45±0.69)mg/L. The levels of Hcy,Lp(a) and hs-CRP in patients with cerebral infarction were significantly higher than those in healthy controls(P<0.05).Conclusion Occurrence of cerebral infarction and Hcy, Lp(a) and hs-CRP levels were closely correlated,so the indexes can be used as risk factors.

Key words: cerebral infarction, homocysteine, lipoprotein(a), high sensitive C-reactive protein, joint detection

CLC Number:

R743

Wang liqiu, Yin changbin, Li jiawei. Clinical significance of joint detection of serum homocysteine, lipoprotein(a) and high sensitive C-reactive protein in cerebral infarction[J]. Journal of Capital Medical University, 2015, 36(5): 782-785.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2015.05.023

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2015/V36/I5/782

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