Value of magnifying endoscopy with blue laser imaging in diagnosis of atrophy and intestinal metaplasia

doi:10.3969/j.issn.1006-7795.2018.05.008

Journal of Capital Medical University ›› 2018, Vol. 39 ›› Issue (5): 663-668.doi: 10.3969/j.issn.1006-7795.2018.05.008

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Value of magnifying endoscopy with blue laser imaging in diagnosis of atrophy and intestinal metaplasia

Wang Jinpeng^1,2, Zhai Huihong¹, Jiao Yue¹, Li Peng¹, Zhang Shutian¹

1. Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University;National Clinical Research Center for Digestive Disease;Beijing Digestive Disease Center;Faculty of Gastroenterology, Capital Medical University;Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing 100050, China;
2. Department of Gastroenterology, Fuxing Hospital, Capital Medical University, Beijing 100038, China

Received:2018-07-31 Online:2018-09-21 Published:2018-10-20
Supported by:
This study was supported by National Natural Science Foundation of China(81570507), National Key R & D Program of the Ministry of Science and Technology(2017YFC0113600), Beijing-Tianjin-Hebei Region Collaborative Innovation Promoting Project Founded by Beijing Science and Technology Commission (Z171100004517009),Beijing Municipal Science & Technology Commission(Z141107002514018).

Abstract

Abstract: Objective To determine the utility of magnifying endoscopy with blue laser imaging(ME-BLI) in diagnosis of atrophy and intestinal metaplasia(IM) among people with risk of atrophy and IM. Methods Patients with risk factors of atrophy or IM underwent ME-BLI from Feb 2017 to Dec 2017. Biopsy was obtained in both atrophic or intestinal metaplasia lesion and gastric mucosal without atrophy or IM. The sensitivity, specificity and accuracy in both atrophy and IM with ME-BLI were calculated. Results The sensitivity, specificity, accuracy, positive and negative predictive value was 93.40%, 71.96%, 79.02%, 62.26% and 95.65% in the diagnosis of atrophy with ME-BLI respectively. The sensitivity, specificity, accuracy, positive and negative predictive value was 100%, 92.07%, 95.94%, 92.31% and 100% in the diagnosis of intestinal metaplasia, respectively. Conclusion The sensitivity, specificity and accuracy with ME-BLI in detection of atrophy and IM were good.

Key words: magnifying endoscopy, blue laser imaging, atrophy, intestinal metaplasia(IM)

CLC Number:

Wang Jinpeng, Zhai Huihong, Jiao Yue, Li Peng, Zhang Shutian. Value of magnifying endoscopy with blue laser imaging in diagnosis of atrophy and intestinal metaplasia[J]. Journal of Capital Medical University, 2018, 39(5): 663-668.

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Value of magnifying endoscopy with blue laser imaging in diagnosis of atrophy and intestinal metaplasia

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