Analyze the etiology of small intestinal bleeding diagnosed by capsule endoscopy

doi:10.3969/j.issn.1006-7795.2020.02.020

Abstract

Abstract: Objective To analyze the clinical and endoscopic characteristics of the patients with suspected small intestinal bleeding and received a capsule endoscopy (CE) and further to explore the etiology. Methods The consecutive patients with suspected of small intestinal bleeding and receiving a CE for the first time at Beijing Shijitan Hospital, Capital Medical University from January 2010 to September 2018 were enrolled. The basic participant characteristics, CE features, clinical diagnosis and etiology were collected for further analysis. Results A total of 93 patients were enrolled, and CE retention was found in one patient (1.1%). The mean age was (59.7±19.4) years, from 14 to 94 years, and 58 patients (62.4%) were the male. The rate of using non-steroid anti-inflammatory drugs (NSAIDs) and hospitalized patients were 39.8% (37/93) and 93.5% (87/93), respectively. The overt gastrointestinal bleeding group patients had higher rate of hospitalized patients, and lower level of hemoglobin (P<0.05). Small intestinal inflammation (53/93) was the most common lesion, followed by intestinal vascular disease (18/93). The etiology of small intestinal bleeding was indentified in 74.2% (69/93) of patients, including 26 cases of NSAIDs enteropathy, 14 of intestinal telangiectasis, 5 of Crohn's disease, 5 of unidentified ulcers, 5 of intestinal lymphangiectasia, 4 of portal hypertension enteropathy, 4 of parasitic disease, 3 of Meckel's diverticulum, 1 of eosinophilic gastroenteritis, 1 of cryptogenic multifocal ulcerous stenosing enteritis, and 1 of intestinal malignant glomus tumor. The etiology was identified in 75.0% (51/68) and 72.0% (18/25) of patients with overt and obscure gastrointestinal bleeding, respectively (P=0.769).Conclusion CE plays an important role in the diagnosis of small intestinal bleeding. Small intestinal inflammation, especially NSAIDs enteropathy, was the most common etiology of small intestinal bleeding in our hospital.

Key words: capsule endoscopy, intestinal bleeding, small intestinal disease, diagnosis, etiology

CLC Number:

Lin Lin, Wu Jing, Liu Kuiliang, Liu Hong, Wang Canghai. Analyze the etiology of small intestinal bleeding diagnosed by capsule endoscopy[J]. Journal of Capital Medical University, 2020, 41(2): 261-266.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2020.02.020

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2020/V41/I2/261

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