Journal of Capital Medical University ›› 2022, Vol. 43 ›› Issue (4): 558-563.doi: 10.3969/j.issn.1006-7795.2022.04.008

• Integrated Diagnosis and Treatment of Lung Cancer • Previous Articles     Next Articles

Diagnostic value of computed tomography guided percutaneous transthoracic needle biopsy (PTNB) for ground-glass nodule

Qian Kun, Zhao Xin, Tan Xiaogang, Tian Xiaoru, Liu Xingsheng, Zhang Yi*   

  1. Department of Thoracic Surgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
  • Received:2022-04-13 Online:2022-08-21 Published:2022-10-28
  • Contact: *E-mail:steven9130@sina.com
  • Supported by:
    This study was supported by Capital Medical Development Research Fund (2022-2-2013).

Abstract: Objective To investigate the diagnostic value of computed tomography(CT) guided percutaneous transthoracic needle biopsy (PTNB) for ground-glass nodule (GGN). Methods The clinicopathological data of 217 patients with GGN who underwent CT guided PTNB from January 2014 to January 2019 were retrospectively analyzed. The cases with malignant puncture were judged to be positive. The patients with benign puncture were clinically diagnosed in combination with the follow-up results, and the puncture pathology was compared with the final clinical diagnosis. The accuracy, sensitivity, negative predictive value, and complication rate of puncture biopsy in each group were statistically analyzed. Results The overall accuracy of 217 patients was 93.5% (203/217), the sensitivity was 92.2% (165/179), and the negative predictive value was 73.1% (38/52). The overall incidence of complications was 35.5%, mainly hemoptysis and pneumothorax. Conclusion CT guided PTNB GGN had high accuracy and sensitivity. It is necessary to be vigilant against false negative results and properly deal with complications.

Key words: ground-glass nodule, biopsy, diagnostic value

CLC Number: