Analysis of clinical characteristics and risk factors of arrhythmia after thoracoscopic pneumonectomy in elderly patients with lung cancer

doi:10.3969/j.issn.1006-7795.2022.04.009

Abstract

Abstract: Objective To investigate the risk factors of arrhythmia in elderly lung cancer patients age≥60 years after thoracoscopic pneumonectomy under general anesthesia. Methods Retrospective analysis was performed on the data of 100 elderly lung cancer patients admitted to Xuanwu Hospital, Capital Medical University from October 2021 to December 2021. Patients diagnosed with concurrent arrhythmia were selected as the observation group (arrhythmia group), and patients diagnosed with non-arrhythmia were selected as the control group (non-arrhythmia group). Univariate and multivariate Logistic regression were used to analyze risk factors. Results The total incidence of arrhythmia in hospitalized patients after thoracoscopic lung cancer resection was 19%. Age, surgical methods, complications and hypertension were independent risk factors for arrhythmia in patients with lung cancer surgery. Conclusion For elderly lung cancer patients, the possibility of postoperative arrhythmia could be inferred by the age, past history of hypertension, postoperative constipation, surgical methods, albumin abnormalities, and then targeted treatment, in order to achieve early diagnosis and prevention of postoperative arrhythmia.

Key words: elderly, thoracoscopy, lung cancer resection, arrhythmia, clinical features, risk factors

CLC Number:

R734.2

Zhang Jingtao, Wang Xinran, Han Binru, Qiang Ying, Liu Xueqi, Zhang Yi. Analysis of clinical characteristics and risk factors of arrhythmia after thoracoscopic pneumonectomy in elderly patients with lung cancer[J]. Journal of Capital Medical University, 2022, 43(4): 564-569.

0
/ / Recommend

Add to citation manager EndNote|Reference Manager|ProCite|BibTeX|RefWorks

URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2022.04.009

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2022/V43/I4/564

References

[1] 张化芝, 郭晓烨, 李晓双, 等. 肺癌术后并发肺部感染的病原学分析及影响因素分析[J]. 中华医院感染学杂志, 2018, 28(1):77－80.
[2] Forde P M, Chaft J E, Smith K N, et al. Neoadjuvant PD－1 blockade in resectable lung cancer[J]. N Engl J Med, 2018, 378(21):1976－1986.
[3] Rolfo C, Mack P C, Scagliotti G V, et al. Liquid biopsy for advanced Non-small cell lung cancer (NSCLC):a statement paper from the IASLC[J]. J Thorac Oncol, 2018, 13(9):1248－1268.
[4] Gonlugur T E, Gonlugur U. Comorbidity as a prognostic factor in small cell lung cancer[J]. Tumori, 2006, 92(5):423－428.
[5] 吕玲, 姜成钢, 兰心刚, 等. 肺癌术后心律失常的相关危险因素分析[J]. 中国医科大学学报, 2012, 41(3):258－261.
[6] 赵嘉华, 初向阳, 薛志强, 等. 352例高龄肺癌术后心律失常的危险因素分析[J]. 中国肺癌杂志, 2011, 14(3):251－255.
[7] 高凤敏, 曹颖平. 诊断学[M]. 北京: 中国医药科技出版社, 2016.
[8] 中华人民共和国国家卫生健康委员会. 癌症疼痛诊疗规范(2018年版)[J]. 临床肿瘤学杂志, 2018, 23(10):937－944.
[9] 张丹, 夏志伟. 功能性便秘的罗马Ⅲ标准[J]. 中国医刊, 2008, 43(12):63－64.
[10] 肖懿慧, 高渊, 吴燕, 等. 肺癌术后房性心律失常的多因素分析[J]. 现代肿瘤医学, 2019, 27(16):2864－2867.
[11] Parayath N N, Parikh A, Amiji M M. Repolarization of Tumor-Associated macrophages in a genetically engineered nonsmall cell lung cancer model by intraperitoneal administration of hyaluronic acid-based nanoparticles encapsulating MicroRNA－125b[J]. Nano Lett, 2018, 18(6):3571－3579.
[12] Thakur M K, Ruterbusch J J, Schwartz A G, et al. Risk of second lung cancer in patients with previously treated lung cancer: analysis of surveillance, epidemiology, and end results (SEER) data[J]. J Thorac Oncol, 2018, 13(1):46－53.
[13] Nomura S, Yokoi T, Kurata T. Platelet-related indices in patients with lung cancer with nivolumab[J]. Platelets, 2018, 29(2):207－208.
[14] Jemal A, Miller K D, Ma J M, et al. Higher lung cancer incidence in young women than young men in the United States[J]. N Engl J Med, 2018, 378(21):1999－2009.
[15] Wu D H, Xu M Y, Mao T, et al. Risk factors for intraoperative atrial fibrillation: a retrospective analysis of 10,563 lung operations in a single center[J]. Ann Thorac Surg, 2012, 94(1):193－197.
[16] 许建宁, 刘国锋. 全胸腔镜术式与开胸肺叶切除术对早期NSCLC患者围手术期的影响[J]. 实用肿瘤杂志, 2017, 32(6):511－514.
[17] Schiller J H. A new standard of care for advanced lung cancer[J]. N Engl J Med, 2018, 378(22):2135－2137.
[18] Vrankar M, Zwitter M, Kern I, et al. PD-L1 expression can be regarded as prognostic factor for survival of non-small cell lung cancer patients after chemoradiotherapy[J]. Neoplasma, 2018, 65(1):140－146.
[19] 郑中龙, 李涛, 卿松. 全程管理体系在肺癌患者术后便秘的预防及治疗中的应用[J]. 黑龙江医学, 2020, 44(8):1013－1015.
[20] Brown T J, Keshvani N, Gupta A, et al. Rates of appropriate laxative prophylaxis for opioid-induced constipation in veterans with lung cancer: a retrospective cohort study[J]. Support Care Cancer, 2020, 28(11):5315－5321.
[21] 何浩, 沙永生, 孔轻轻. 肺癌患者全肺切除术后并发心律失常的原因分析及护理对策[J]. 护士进修杂志, 2013, 28(11):1011－1014.