Analysis on risk factors of adverse events after non-sedated esophagogastroduo-denoscopy

doi:10.3969/j.issn.1006-7795.2025.04.014

Abstract

Abstract: Objective To investigate the risk factor for adverse events(AEs) after non-sedated esophagogastroduodenoscopy (EGD). Methods The data on clinical manifestations, adverse events after non-sedated EGD and common risk factors were collected and retrospectively analyzed with statistical methods in patients who underwent non-sedated EGD from May 2018 to June 2019. These patients were divided into AEs group and non-AEs group. Results Of 2 384 patients, 57.67%(1 375/2 384) presented with nausea, 12.79%(305/2 384) vomiting, and 5.79%(138/2 384) presented with pharyngalgia. Multivariate Logistic regression analysis was performed. Advanced age(≥65 years old) (OR=0.683, 95%CI:0.506-0.921) was protective factors for nausea after non-sedated EGD. Hypertension (OR=1.361,95%CI:1.026-1.806), overweight (OR=1.399,95%CI:1.154-1.695), obesity(OR=2.594,95% CI:1.760-3.823) and inspection duration ＞15 min (OR=3.107, 95%CI:2.296-4.206) were independent risk factors for nausea after non-sedated EGD. Advanced age (OR=0.393, 95%CI: 0.221-0.699) and imported equipment (OR=0.697, 95%CI:0.546-0.890) were protective factors for vomiting after non-sedated EGD. Moreover, inspection duration ＞15 min (OR=1.641, 95%CI:1.008-2.699) was independent risk factors for vomiting after non-sedated EGD. There was no difference in success rate of non-sedated EGD between two groups(P<0.05). Conclusion Hypertension, overweight and obesity were independent risk factors for nausea after non-sedated EGD. The advanced age and imported equipment were protective factors for vomiting after non-sedated EGD. In addition, inspection duration over 15 min is a risk factor for AEs such as nausea and vomiting after nonsedative EGD. Whether AEs occurred or not is non-related to success rate of non-sedated EGD.

Key words: esophagogastroduodenoscopy, non-sedated, risk factors, adverse events, domestic endoscopy, Logistic regression analysis

CLC Number:

R573

Yang Shuyue, Liu Sifan, Ji Xu, Zhao Mengran, Zhang Zheng, Li Peng. Analysis on risk factors of adverse events after non-sedated esophagogastroduo-denoscopy[J]. Journal of Capital Medical University, 2025, 46(4): 676-681.

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