Abstract: Objective To investigate the association between sleep efficiency and diabetes mellitus (DM) in obstructive sleep apnea syndrome (OSA) and primary snoring patients. Methods A total of 3 124 patients who received sleep monitoring in the Sleep Medical Center of Xuanwu Hospital, Capital Medical University from October 2002 to September 2021 were retrospectively analyzed. Sleep efficiency was divided into grade 1 (≥85%), grade 2 (80%-84.9%), and grade 3 (<80%). All participants were divided into OSA group and simple snoring group with apnea hypopnea index (AHI)≥5 times/h. Multivariate Logistic regression models were utilized to investigate the association between sleep quality and diabetes mellitus. Results In OSA patients, after adjusting for potential confounding factors, compared with sleep efficiency ≥ 85%, the prevalence of DM in sleep efficiency < 80% group was significantly higher (OR=1.563, 95%CI:1.005-2.431, P=0.047), but there was no significant difference in primary snoring group (OR=0.957, 95%CI:0.509-1.799, P=0.891). Conclusion There is a significant correlation between poor sleep efficiency and the incidence of DM in OSA patients.

Key words: sleep efficiency, diabetes mellitus, obstructive sleep apnea syndrome