Journal of Capital Medical University ›› 2000, Vol. 21 ›› Issue (1): 29-32.

• 论著 • Previous Articles     Next Articles

Study on the Curative Effect on Cerebral Ischemia in Gerbils with the Danggui Complex Mixture

Feng Lianze1, Yang Liping1, Yang Lianxue2, Wang Wei2, Liu Qian2, Sun Xia2, Lu Houzhen2   

  1. 1. Department of Anatomy of Beijing Medical Staff College;2. Department of Anatomy, Capital University of Medical Sciences
  • Received:1999-08-20 Revised:1900-01-01 Online:2000-01-15 Published:2000-01-15

Abstract: In order to observe the curative effect on cerebral ischemia in the gerbils with the Danggui (Angelica sinensis) complex mixture, the change of the study and memory ability of the gerbils in the cerebral ischemic model group was observed by means of the shuttle box. Morphological change in their hippocampal tissues was observed under the microscopes. The sections of the hippocampal tissue were made use of routine HE, Nills staining. After ligating their unilateral carotid, the memory ability of the gerbils in the model group was significantly lower than that in the preopertive normal value (P<0.01). The regain of memory ability of the gerbils in the treated group with the traditional Chinese medicine (n= 24) was significantly faster than that in the control group (n= 24) (P<0.01). The hippocampal tissue in the model group showed the pathological harm. The pyramid cells of hippocampus in the model group were less than that in the normal group (P<0.01), and the pyramid cells in the treated group were more than those in the control group (P<0.01). The result showed that the Danggui complex mixture could reduce the cerebral pathological harm,promote to regain the physiologic function of postischemic brain,improve the cerebral circulation, and protect on the brain.

Key words: Danggui (Angelica sinensis) complex mixture, cerebral ischemia, Mongolian gerbil

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