Abstract: Objective There was severe pain after the operation of uvulopalatopharyngoplasty(UPPP) for the patients suffered from obstructive sleep apnea syndrome(OSAS).It was necessary to give the analgesia for those patients.The patient-controlled analgesia(PCA) was performed with tramadol or fentanyl for those patients.Methods 42 adult male patients were divided into two groups,tramadol(24) or fentanyl(18) group randomly.The pain score(VAS) of those patients at rest and swallow were observed at the time points as follows: the time of 6 h,the next morning,24 h and 48 h after the operation.The total press number,the total amount of drug on PCA modal,the sedation score during the 24 h postoperative,the PONV and dizziness were also recorded.Results The pain score at both rest and swallow state had no difference at different times after the operation between the two groups.The total numbers of press in tramadol group were significant less than those in fentanyl group at the time of 24 h and 48 h after the operation.The total amount of drug is(593.56±198.71)mg in tramadol group,while that in fentanyl group is(864.58±402.9)μg.At the time of 24 h after the operation,the number of patients whose Ramsey score is zero,in tramadol group is 75%,while that in fentanyl group is 44.4%.There is no difference between the two groups in PONV and dizziness.Conclusion PCA is a good method for the OSAS patients postoperation of the UPPP in terms of pain relieving.The analgesia with tramadol and fentanyl can both gain satisfied effects.

Key words: OSAS, UPPP, PCA, tramadol, fentanyl