Automated mode in the weaning of mechanical ventilated patients: a systematic review

doi:10.3969/j.issn.1006-7795.2013.02.006

Abstract

Abstract:

Objective To investigate the effects of automated weaning mode on the total duration of mechanical ventilation, weaning duration, mortality, length of stay in the intensive care unit and hospital, and adverse events. Methods We searched PubMed, EMBASE, CINAHL, CENTRAL, SinoMed and ISI Web of knowledge, and reference list of articles. We included randomized and quasi-randomized controlled trials comparing automated with non-automated mode in the weaning from mechanical ventilation in critically ill adults. The quality of included studies was critically evaluated and quantitatively analyzed. Results Thirteen trials met the inclusion criteria. Compared with non-automated mode, the duration of mechanical ventilation and weaning in the weaning automated group was reduced significantly [MD=-63.98, 95%CI(-108.67, -19.29)] and [MD=0.84, 95%CI(-1.31, 2.99)], respectively in the mechanical ventilation <24 h subgroup. The re-intubation rate and requirement for protracted weaning over 14 days were significant in the mechanical ventilation <24 h subgroup. Conclusion There is evidence of a reduction in the duration of mechanical ventilation, weaning, and adverse events when automated mode are used. As a result of significant heterogeneity among studies, our findings should be interpreted with caution.

Key words: mechanical ventilators, ventilator weaning, computer-assisted therapy, Meta-analysis

CLC Number:

ZHU Bo, LI Zhiqiang, XI Xiuming. Automated mode in the weaning of mechanical ventilated patients: a systematic review[J]. Journal of Capital Medical University, 2013, 34(2): 191-200.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2013.02.006

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2013/V34/I2/191

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