Journal of Capital Medical University ›› 2002, Vol. 23 ›› Issue (2): 105-106.

• 基础研究 • Previous Articles     Next Articles

Study of Progesterone Receptor in Extracted Tissue after Mifepristone Induced Abortion

Liang Yuanjing1, Xu Qing1, Zhu Dingshou1, Fang Jingyan 2   

  1. 1. Department of Anatomy, Capital University of Medical Sciences;2. Department of Obstetrics and Gynecology, Xuanwu Hospital, Affiliate of Capital University of Medical Sciences
  • Received:2001-09-13 Revised:1900-01-01 Online:2002-04-15 Published:2002-04-15

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Abstract: It is reported that remaining decidua and villi are found in the uterus of some patients who have uterogenic bleeding after mifepristone induced abortion. The purpose was to study the expression of progesterone receptor(PR)in these remaining tissues(n=19)by immunocytochemical LSAB methods. PR was mainly distributed in glandular epithelium, peripheral musculodermic cells, endometrial stroma cells, vesicular endothelium and musclar cells in uterus. These tissue showed positive or strong positive. The remaining chorion villi showed weak positive. Decidual showed negative, despite a few positive cells that were extra-chorion trophoblast and vescular endothelium. PR in the endometrium and decidua were significantly different(P<0.01). This study indicates that the residue of decidua and villi after mifepristone induced abortion are not caused by PR in these tissues.

Key words: progesterone receptor|mifepristone induced abortion|immunocytochemistry

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