Abstract: Obviously the morbidity of severe cranial injury combining gastrointestinal hemorrhage had dropped, the effect of the conservative treatment of severe hemorrhage had greatly improved, with the improvement of the acid-inhibition drug and wide use of parenteral nutrient. The morbidity of severe cranial injury combining gastrointestinal hemorrhage could be reduced obviously with preventive use of acid-restrained drug. The patient with hemorrhage could be treated with the combination of acid-restrained drug, gastric mucosa protective agent and parenteral nutrient. The treatment could mostly stop blooding and operation is not needed.

Key words: severe cranial injury, gastrointestinal hemorrhage, treatment