Journal of Capital Medical University ›› 2014, Vol. 35 ›› Issue (1): 41-44.doi: 10.3969/j.issn.1006-7795.2014.01.010

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Recent advances in studies on the role of sympathetic nerve in lumbar discogenic pain

Tang Yuanzhang1, Bian Jingjing2, Ni Jiaxiang1   

  1. 1. Department of Pain Management, Xuanwu Hospital, Capital Medical University, Beijing 100053, China;
    2. Department of Anesthesiology, The Affiliated Hospital of Xuzhou Medical College, Xuzhou 221000, Jiangsu Province, China
  • Received:2013-12-20 Online:2014-02-21 Published:2014-02-21

Abstract:

Intervertebral disc disorder is a common cause for pain syndroms. Disc degeneration, annular tear, leakage of nucleus pulposus and the nerve ingrowth into the disc dominate the primary reason for discogenic pain. Recent studies on discogenic pain have provided new knowledge about this condition. The lumbar intervertebral disk may be innervated non-segmentally through the paravertebral sympathetic nerves. The exposure of the nucleus pulposus to the outer annulus fibrosus may induce nerve inflammation and ingrowth into the disc. Thus, sympathetic nerves irritation resulting from disc disorder has attached increasing attention to discogenic pain. This review focused on the sympathetic innervations into degenerated disc and the mechanisms of discogenic pain.

Key words: lumbar discogenic, sympathetic nerve, pain

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