Analysis on clinicopathologic characteristics of lymphoid and hemopoietic tissue proliferation disease in orbital and ocular adnexal

doi:10.3969/j.issn.1006-7795.2014.06.021

Abstract

Abstract: Objective To study the clinicopathologic characteristics of lymphoid and hemopoietic tissue proliferation disease in orbital and ocular adnexal. Methods Clinical manifestations and the characteristics of clinicopathology were analyzed retrospectively in two hundreds and ten patients suffering from lymphoid and hemopoietic tissue proliferation in orbital and ocular adnexal. Results The most common histologic type in orbital and ocular adnexa is primary extraocular non-Hodgkin's lymphoma, secondly was Mikuliczs disease and inflammatory pseudotumor. There is a characteristic in age and gender among the various types of this group, and there is an overlap in clinicopathologic characteristics. The most common histologic subtype was extraocular marginal zone lymphoma of mucosa-associated lymphoid tissue type in extraocular non-Hodgkin's lymphoma, which accounted for 74.0%(74/100 cases)of cases. The extraocular marginal zone lymphoma of mucosa-associated lymphoid tissue type has different traits from that at other sites. Immunohistochemical staining is very important to the diagnosis and differential diagnosis for lymphoid and hemopoietic tissue proliferation disease in this site. The unique feature in diagnosis and clinicopathology is obvious to IgG4-related disease of this site. Conclusion We conclude that lymphoid and hemopoietic tissue proliferation disease in orbital and ocular adnexal is common among patients. There is a characteristic in age, gender and histologic subtype, which is helpful to understand these characteristics for pathological diagnosis.

Key words: orbital and ocular adnexal, lymphoid and hemopoietic tissue proliferation disease, extraocular marginal zone lymphoma of mucosa-associated lymphoid tissue type, IgG4-related disease, clinicopathology

CLC Number:

R267.7

He Xiaojin, Xing Li. Analysis on clinicopathologic characteristics of lymphoid and hemopoietic tissue proliferation disease in orbital and ocular adnexal[J]. Journal of Capital Medical University, 2014, 35(6): 790-797.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2014.06.021

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2014/V35/I6/790

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