Common clinical manifestations of AIDS complicated with Pneumocystis pneumonia and the diagnostic value of a plasma 1.3-β-D-glucan test

doi:10.3969/j.issn.1006-7795.2016.04.018

Abstract

Abstract: Objective To investigate the common clinical manifestations of acquired immune deficiency syndrome (AIDS) complicated with Pneumocystis pneumonia and clinical value of plasma 1, 3-β-D-glucan (G) test in diagnosis of the Pneumocystis pneumonia in patients with AIDS. Methods This was a retrospective study on 83 human immunodeficiency virus (HIV)/AIDS patients with pulmonary infection in the ward of infectious diseases in Beijing Youan Hospital from April to September 2015. The results of G test were analyzed. Results receiver operating characteristic curve (ROC) analysis showed that the areas under the curve of G test was 0.836. The sensitivity and specificity of G-test were 86.36% and 84.61%; the positive predictive value (PPV) and negative predictive value (NPV) were 86.36% and 84.61%. Conclusion The levels of plasma 1, 3-β-D-glucan (G) could provide an effective laboratory diagnostic reference for Pneumocystis pneumonia in patients with AIDS.

Key words: 1,3-β-D-glucan (G)test, acquired immune deficiency syndrome, Pneumocystis pneumonia, diagnosis

CLC Number:

R512.91

Huang Shujing, Chen Ming, Dai Fangfang, Yu Yanhua, Ding Xiurong, Feng Xia, Lou Jinli, Li Hongjun. Common clinical manifestations of AIDS complicated with Pneumocystis pneumonia and the diagnostic value of a plasma 1.3-β-D-glucan test[J]. Journal of Capital Medical University, 2016, 37(4): 504-508.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2016.04.018

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2016/V37/I4/504

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