Effects of the structured rehabilitation skills training program in the improvement of depressive symptoms and quality of life in patients with major depressive disorder

doi:10.3969/j.issn.1006-7795.2018.05.003

Journal of Capital Medical University ›› 2018, Vol. 39 ›› Issue (5): 636-640.doi: 10.3969/j.issn.1006-7795.2018.05.003

Effects of the structured rehabilitation skills training program in the improvement of depressive symptoms and quality of life in patients with major depressive disorder

Tang Lirong^1,2, Zheng Wei³, Zhao Xiuqin^1,2, Ren Yanping^1,2, Xiang Yingqiang^1,2, Gao Yue^1,2, Xu Qiuyue^1,2, Ma Xin^1,2

1. Beijing Key Laboratory of Diagnosis and Treatment of Mental Disorder, National Clinical Research Center for Mental Disorders, Department of Clinical Psychology, Beijing Anding Hospital, Capital Medical University, Beijing 100088, China;
2. Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing 100069, China;
3. Department of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University(Guangzhou Huiai Hospital), Guangzhou 510370, China

Received:2018-04-03 Online:2018-09-21 Published:2018-10-20
Supported by:
This study was supported by Major State Basic Research Development Program of China (2014CB744601),Beijing Science and Technology Program of Beijing Science and Technology Commission(Z13110000261300,D101107047810004),Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding (ZYLX201815),Medicine and Clinical Cooperative Research Program of Capital Medical University (17JL36).

Abstract

Abstract: Objective To examine the effects of the structured rehabilitation skills training program on the improvement of depressive symptoms and quality of life in patients with major depressive disorder (MDD). Methods A total of 212 patients with MDD who met the inclusion criteria of this study were divided into two groups, namely intervention group (conventional treatment combined with the whole rehabilitation skills training program, n=102) and control group (conventional treatment combined with general health education, n=110). Depressive symptoms and quality of life were assessed using HAMD-17 (Hamilton Depression Rating Scale for Depression-17 item), WHOQOL-BREF (World Health Organization's Quality of Life Instruments-Abbreviated Version) at baseline and at every follow-up visit in 1 year(every 3 months). All outcomes were analyzed using SPSS 17.0 software. Results The difference between groups and intra-group differences of HAMD-17 total score and each factor score and total score of WHOQOL-BREF were statistically significant. HAMD-17 total score in intervention group are significantly lower than that in control group at 3nd, 6th, 9th and 12th month. Total score and each factor score of WHOQOL-BREF in intervention are significantly higher than that in control group at 6th, 9th and 12th month. Conclusion Skills training program for patients with major depressive disorder established in this study is mostly reasonable, and it is effective in improving depressive symptoms and life quality.

Key words: major depressive disorder, rehabilitation, skills training program, quality of life

CLC Number:

R749

Tang Lirong, Zheng Wei, Zhao Xiuqin, Ren Yanping, Xiang Yingqiang, Gao Yue, Xu Qiuyue, Ma Xin. Effects of the structured rehabilitation skills training program in the improvement of depressive symptoms and quality of life in patients with major depressive disorder[J]. Journal of Capital Medical University, 2018, 39(5): 636-640.

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Effects of the structured rehabilitation skills training program in the improvement of depressive symptoms and quality of life in patients with major depressive disorder

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