Impact of hormone therapy on quality of life of women with menopausal syndrome

doi:10.3969/j.issn.1006-7795.2013.03.020

Abstract

Abstract:

Objective To evaluate the effects of hormone replacement therapy on climacteric patient's physical condition as well as psychology.Methods An observational study on 125 patients with climacteric syndrome was conducted, the patients were divided into two groups according to whether they were treated with hormone therapy: group A had 65 patients without any hormone therapy, group B had 60 patients who received hormone replacement therapy for 6 months; the basic parameters and complete Kupperman scale, Self-Rating Anxiety Scale (SAS), Self-Rating Depression Scale (SDS) and Menopause-specific Quality of Life Questionnaire (MENQOL) were applied for evaluation.Results In the 60 patients with menopausal syndrome who received hormone replacement therapy, the scores of Kupperman index, SAS, SDS, MENQOL were significantly lower than those of the untreated patients' group; of whom 35 patients showed significant difference between the scores obtained before and after treatment in 4 scalel. Conclusion Hormone replacement therapy could significantly alleviate the perimenopausal physical discomfort, but also could improve anxiety and depression,therefore,could improve the quality of life of menopausal women.

Key words: menopause, quality of life, hormone replacement therapy

CLC Number:

R 246.3

YIN Dongmei, LIU Zhen, Ruan Xiangyan, WANG Juan. Impact of hormone therapy on quality of life of women with menopausal syndrome[J]. Journal of Capital Medical University, 2013, 34(3): 428-431.

0
/ / Recommend

Add to citation manager EndNote|Reference Manager|ProCite|BibTeX|RefWorks

URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2013.03.020

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2013/V34/I3/428

References

[1] Llaneza P, García-Portilla M P, Llaneza-Suárez D,et al. Depressive disorders and the menopause transition. Maturitas,2012,71(2):120-130.

[2] Baldinger P, Kranz G, Hflich A,et al.The effects of hormone replacement therapy on mind and brain[J].Nervenarzt,2013,84(1):14-19.

[3] Baldinger P, Kranz G, Hflich A,et al. Effect of estrogen replacement therapy on symptoms of depression and anxiety in non-depressive menopausal women: a randomized double-blind, controlled study[J]. Arch Womens Ment Health,2011,14(6):479-486.

[4] 中华医学会妇产科学分会绝经学组.绝经过渡期和绝经后期激素补充治疗临床应用指南(2009版)[J].中华妇产科杂志,2010,45(8):635-638.

[5] 葛秦生,田秦杰.实用女性生殖内分泌学[M].北京:人民卫生出版社,2008:296.

[6] 曹泽毅.中华妇产科学[M]. 2版. 北京:人民卫生出版社,2004:2530-2554.

[7] Whiteley J, Wagner J S, Bushmakin A,etal. Impact of the severity of vasomotor symptoms on health status, resource use, and productivity[J]. Menopause, 2013,20(5):518-524.

[8] Shyu Y K, Pan C H, Liu W M. Health-related quality of life and healthcare resource utilization in Taiwanese women with menopausal symptoms: a nation-wide survey[J]. Nurs Res,2012,20(3):208-218.

[9] Terauchi M, Hiramitsu S, Akiyoshi M, Associations among depression, anxiety and somatic symptoms in peri- and postmenopausal women[J]. Obstet Gynaecol Res,2013,39(5):1007-1013.

[10] Ayers B, Hunter M S.Climacteric. Health-related quality of life of women with menopausal hot flushes and night sweats[J]. Climacteric,2013,16(2):235-239.

[11] Studd J.Ten reasons to be happy about hormone replacement therapy: a guide for patients[J]. Menopause, 2010,16(1):44-46.

[12] 洪宇,彭瑾,谢梅青.围绝经期情绪障碍诊断与治疗的研究进展[J].实用妇产科杂志,2011,27(9):658-660.

[13] 邱忠君, 马素慧, 李丹,等.慢性疾病与围绝经期综合征的关系[J].中国煤炭工业医学杂志,2012,15(8):1174-1175.

[14] 黄维站, 崔孝菊.女性更年期抑郁症心理干预的效果分析[J].中国煤炭工业医学杂志,2011,14(6):916-918.

[1]	Ju Rui, Ruan Xiangyan, Dai Yinmei, Bai Yongtao, Yang Yu, Xu Xin, Cheng Jiaojiao, Yang Xingzi, Shi Yanhong, Sun Yanhua, Li Ruiling. Influencing factors of female sexual dysfunction in Chinese women [J]. Journal of Capital Medical University, 2022, 43(3): 357-363.
[2]	Xu Xin, Ruan Xiangyan, Ju Rui, Yang Yu, Cheng Jiaojiao, Wang Zhikun, Alfred O. Mueck. Relationship between mild cognitive impairment and menopausal symptoms in Chinese women [J]. Journal of Capital Medical University, 2022, 43(3): 369-374.
[3]	Ju Rui, Ruan Xiangyan, Dai Yinmei, Bai Yongtao, Yang Xingzi, Shi Yanhong, Xu Xin, Yang Yu, Cheng Jiaojiao, Sun Yanhua, Li Ruiling. Study on the situation of female sexual dysfunction in different reproductive aging stages and postmenopausal women using hormone replacement therapy [J]. Journal of Capital Medical University, 2021, 42(4): 533-539.
[4]	Liu Yijun, Lin Xiangying, Zhang Yan. Validity and reliability of the Chinese version ofWorld Health Organization Quality of Life-BREF among patients with end-stage renal disease [J]. Journal of Capital Medical University, 2021, 42(4): 635-641.
[5]	Ju Rui, Ruan Xiangyan, Xu Xin, Yang Yu, Zhang Luping, Qin Shuang, Wang Binhong, Dou Zhuli, Alfred O. Mueck. Prevalence of female sexual dysfunction and the relationship between climacteric symptoms and female sexual dysfunction in Chinese women with menopause transition stage and postmenopausal stage [J]. Journal of Capital Medical University, 2020, 41(4): 503-507.
[6]	Li Muchan, Xu Chunjun, Wang Yutao, Wang Cong. Clinical study on improving the quality of life in patients with early and middle stages hepatocellular carcinoma [J]. Journal of Capital Medical University, 2019, 40(3): 352-357.
[7]	Wang Rui, Song Nan, Zhu Hong, Jia Hongxiao. Study on quality and satisfaction of life and the social function in patients with depersonalization disorder [J]. Journal of Capital Medical University, 2019, 40(2): 214-219.
[8]	Tang Lirong, Zheng Wei, Zhao Xiuqin, Ren Yanping, Xiang Yingqiang, Gao Yue, Xu Qiuyue, Ma Xin. Effects of the structured rehabilitation skills training program in the improvement of depressive symptoms and quality of life in patients with major depressive disorder [J]. Journal of Capital Medical University, 2018, 39(5): 636-640.
[9]	Zhu Hong, Zhi Lihua, Jia Hongxiao. Evaluating the efficacy of ziprasidone in improving cognition,quality of life and clinical symptom in schizophrenia [J]. Journal of Capital Medical University, 2018, 39(2): 199-203.
[10]	Li Xue, Ruan Xiangyan, Wang Husheng, Li Yanglu, Zhao Yue, Gu Muqing, Du Juan, Song Jinghua, Jin Fengyu, Alfred O. Mueck. Effects of primary ovarian insufficiency on glucose and lipid metabolism and biochemical parameters in patients [J]. Journal of Capital Medical University, 2017, 38(4): 504-508.
[11]	Li Feng, Bo Qijing, Zhao Yan, Liu Hui, Wang Chuanyue. Quality of life and related factors in patients with major depressive disorder [J]. Journal of Capital Medical University, 2017, 38(2): 186-191.
[12]	Sun Yange, Ruan Xiangyan, Alfred O. Mueck. Change of cardiovascular disease risk factors in perimenopausal and postmenopausal women [J]. Journal of Capital Medical University, 2016, 37(4): 413-417.
[13]	Fang Ying, Hong Liming, Yang Xiaokui. A gonadotrophin-releasing hormone agonist(GnRHa) suppression protocol versus normal hormone replacement therapy(HRT) protocol in multiple implantation failed patients undergoing frozen-embryo transfer cycles [J]. Journal of Capital Medical University, 2015, 36(4): 544-547.
[14]	Cui Yamei, Ruan Xiangyan, Tian Xuanxuan, Zhang Ying, Wu Hongqin, Liu Yulan, Zhen Jie, Diethelm Wallwiener, Alfred O. Mueck. Investigation on the prevalence of menopausal symptoms of women in Beijing Obstetrics and Gynecology Hospital [J]. Journal of Capital Medical University, 2014, 35(4): 392-396.
[15]	Ruan Xiangyan, Cui Yamei, Diethelm Wallwiener, Alfred O. Mueck. Menopause hormone therapy and risk of metabolic syndrome [J]. Journal of Capital Medical University, 2014, 35(4): 387-391.