Journal of Capital Medical University ›› 2009, Vol. 30 ›› Issue (2): 235-238.

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Botulinum Toxin A Combining Home Rehabilitation for the Treatment of Spastic Cerebral Palsy

GAO Bao-qin1, WANG Gui-fen1, WANG Ya-jie1, DENG Ya-xian1, YANG Li-ying1, YANG Wei-li1, DENG Xin1, TIAN Zhao-xia1, HUANG Hai-tao1, XIE Tian1, ZHOU Da-wei2, XU Jing2   

  1. 1. Department of Pediatrics, Beijing Tiantan Hospital, Capital Medical University;2. Artificial Extremities and Orthopedic Technique Specialty Secondary School, Ministry of Civil Affair
  • Received:2008-02-18 Revised:1900-01-01 Online:2009-04-21 Published:2009-04-21

Abstract:

Objective To observe the curative effects and economical values of botulinum toxic A(BTX-A) combining home rehabilitation for treatment of spastic cerebral palsy(CP). As well as the application of gait analysis apparatus for the effective treatment of CP. Methods One hundred and forty eight children with CP were randomly divided into treatment group (83 cases) and control group(65 cases), and choose another 30 children with normal exercise and non-cerebral palsy as normal group. The treatment group received intramuscular injection of BTX-A and home rehabilitation. The control group received rehabilitation by professional physicians. Physician rating scale(PRS) and medical cost of both groups were assessed. Using gait analysis test platform, 30 cases of the treatment group received effectiveness evaluation before and 1 month after therapy. Results The PRS of treatment group on 3, 6 months after therapy improved more significantly than the control group(P<0.000). The cost in the treatment group was less than that of the control group(P<0.000). The ankle, knee joint movements and gait speed in the treatment group improved more significantly(P<0.000). Conclusion Rehabilitation combining intramuscular injection of BTX-A was better than single rehabilitation and its cost is lower than professional rehabilitation. It is objective, reliable and accurate in evaluating the curative effect with gait analysis apparatus.

Key words: cerebral palsy, botulinum toxic A, rehabilitation training

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