Observation of the therapeutic effect of hyperbaric oxygen on refractory interstitial cystitis/bladder pain syndrome

doi:10.3969/j.issn.1006-7795.2020.03.022

Abstract

Abstract: Objective To investigate the clinical efficacy of hyperbaric oxygen (HBO) in the treatment of refractory interstitial cystitis/bladder pain syndrome (IC/BPS). Methods Three-day voiding diary was recorded before HBO treatment and 1, 3 and 6 months after HBO treatment in patients with IC/BPS, and the O'leary-Sant score, visual analogue scale (VAS), quality of life index (QoL), pelvic pain, urgency and frequency (PUF) score were evaluated. Bladder capacity, "erythema sign" and ulcer were evaluated before and 6 months after treatment.Results Totally 19 patients, compared with those before treatment, the 24-hour urination frequency (11.37±1.98), nighttime urination frequency (1.53±1.17), O'leary-Sant score (15.95±2.80), VAS (31.79±9.53), QoL (2.11±0.74), PUF score (16.16±4.39) and bladder capacity (347.53±75.28) mL of the patients after 6 months of treatment improved significantly (P<0.05, respectively).There were also significant differences in 24-hour urination frequency, O'leary-Sant score, and VAS among different follow-up periods (P_time<0.01). In addition, 7 patients with "erythema sign" turned into negative and 3 patients with ulcers healed.Conclusion HBO is effective in the treatment of refractory IC/BPS.

Key words: interstitial cystitis/bladder pain syndrome, hyperbaric oxygen, symptom scores

CLC Number:

R694+.3

Zhang Jing, Wu Liyang, Yang Jing, Zhang Peng. Observation of the therapeutic effect of hyperbaric oxygen on refractory interstitial cystitis/bladder pain syndrome[J]. Journal of Capital Medical University, 2020, 41(3): 444-448.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2020.03.022

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2020/V41/I3/444

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