The gain value of pinhole collimator in parathyroid imaging

doi:10. 3969/ j. issn. 1006-7795. 2024. 01. 005

Abstract

Abstract: Objective To explore the gain value of pinhole collimator planar imaging in the diagnosis of parathyroid imaging. Methods Retrospective analysis was performed on 55 patients with clinically diagnosed hyperparathyroidism（HPT） who underwent surgical treatment from July 2017 to July 2019. All patients underwent 99mTc-sestamibi（^99mTc-MIBI） dual phase planar imaging (pinhole collimator,parallel hole collimator) combined with delayed phase single photon emission computed tomography/computed tomography（SPECT/CT）imaging. With surgical pathological results as the “gold standard”,the sensitivity,specificity and accuracy of detecting parathyroid lesions in parallel hole plane imaging (group A),SPECT/CT (group B),parallel hole +SPECT/CT (group C),pinhole plane imaging (group D),and pinhole + parallel hole +SPECT/CT (group E) were calculated by SPSS 26.0 statistical software. The diagnostic efficacy of each group was compared by χ2 test. Results A total of 79 parathyroid lesions were found in 55 hyperparathyroidism patients,of which 40 were single lesions and 15 were multiple lesions. The 79 parathyroid lesions included 29 adenomas,15 adenomatous hyperplasia,and 35 hyperplasia; two of these lesions were ectopic (1 retrosternal adenoma and 1 retrosternal hyperplasia); the 11 patients had 11 thyroid lesions,4 papillary thyroid carcinoma,2 thyroid adenomas,1 thyroid adenomatous hyperplasia,and 4 nodular goiter. A total of 53 positive lesions were found in parallel hole C group,and 14 additional positive lesions were found after pinhole plane imaging. The sensitivity and accuracy of group E were significantly higher than those of group A (χ²=64.168，P<0.001；χ²=45.182，P<0.001),group B (χ²=50.452，P<0.001；χ²=36.847，P<0.001), and group C (χ²=43.636，P<0.001；χ²=20.502，P<0.001);there was no statistical difference in sensitivity and accuracy between group E and group D（P>0.05）;there was no statistical difference in specificity between the 5 groups（P>0.05）. Conclusion The pinhole collimator planar imaging could improve the sensitivity and accuracy of parathyroid imaging.

Key words: hyperparathyroidism, single photon emission computed tomography/computed tomography, sestamibi, pinhole collimation

CLC Number:

R582.1
R81

Li Meng, Li Mei, Luo Sha, Wang Shuang, Zhang Juan, Luo Shiyu, Xian Junfang. The gain value of pinhole collimator in parathyroid imaging[J]. Journal of Capital Medical University, doi: 10. 3969/ j. issn. 1006-7795. 2024. 01. 005.

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