Abstract: In response to the core bottleneck issue of the significantly low conversion rate of medical science and technology achievements in China, in this article we deeply analyze the root cause which lie in the serious lack of industrialization orientation, especially the insufficient efficient screening in the proof-of-concept (PoC) stage. The research proposes to build a new type of medical PoC platform system oriented towards industry as the solution. This system takes market demand as the anchor point, and through establishing a pre-demand assessment mechanism, building a vertical professional platform matrix covering core and frontier fields, and innovatively designing a dynamic benefit-sharing and risk-sharing mechanism of “five-party linkage of government, industry, academia, research and medicine”. The platform integrates core functional modules such as intelligent assessment and incubation, capital collaboration, technology acceleration, dual drive of clinical and market, compliance risk control, and industrial ecosystem. It is expected to significantly enhance the efficiency of medical technology transfer, shorten the industrialization cycle, and drive the incubation of compound talents and the construction of an industrial collaborative ecosystem, providing a systematic solution for breaking through the “first mile” of medical technology transfer.

Key words: biomedicine, biopharmaceutical industry, medical technology, technology transfer, proof of concept, innovation