| [1] Alzheimer's Association. 2012 Alzheimer's disease facts and figures[J]. Alzheimers Dement, 2012,8(2):131-168.[2] Goedert M, Spillantini M G. A century of Alzheimer's disease[J]. Science, 2006,314(5800):777-781.[3] Faivre E, Hölscher C. Neuroprotective effects of D-Ala2GIP on Alzheimer's disease biomarkers in an APP/PS1 mouse model[J]. Alzheimers Res Ther, 2013,5(2):20.[4] 赵丽波,付宏娟,张健莉.阿尔茨海默病发生机制的研究进展[J].中国老年学杂志,2011,31(24):4997-4998.[5] Viola K L, Velasco P T, Klein W L. Why Alzheimer's is a disease of memory: the attack on synapses by A beta oligomers(ADDLs)[J]. J Nutr Health Aging, 2008,12(1):51S-7S.[6] 姜新,谢明,白丽娟,等.PGN激活BV2内吞Aβ寡聚体后对PC12的影响[J].首都医科大学学报,2011,32(4):509-513.[7] 刘晓杰,杨威,祁金顺.氧化应激与阿尔茨海默病[J].生理学报,2012,64(1):87-95.[8] 杜怡峰,闫鹏,韩晓娟.Alzheimer病胰岛素信号传导通路的研究[J].济宁医学院学报,2012,35(2):84-92.[9] 陈逸,张宝荣.阿尔茨海默病相关核心生物标志物研究进展[J].生命科学,2014,26(1):2-8.[10] Blennow K, Hampel H. CSF markers for incipient Alzheimer's disease[J]. Lancet Neurol, 2003,2(10):605-613.[11] 王玲,朱鸣峰.阿尔茨海默病发病机制的研究进展[J].吉林医学,2013,34(3):531-532.[12] Xiao A W, He J, Wang Q, et al. The origin and development of plaques and phosphorylated tau are associated with axonopathy in Alzheimer's disease[J]. Neurosci Bull, 2011,27(5):287-299.[13] Sakono M, Zako T. Amyloid oligomers: formation and toxicity of Abeta oligomers[J]. FEBS J, 2010,277(6):1348-1358.[14] El Khoury N B, Gratuze M, Papon M A, et al. Insulin dysfunction and Tau pathology[J]. Front Cell Neurosci, 2014,8:22.[15] Hussain I, Powell D J, Howlett D R, et al. ASP1(BACE2) cleaves the amyloid precursor protein at the beta-secretase site[J]. Mol Cell Neurosci, 2000,16(5):609-619.[16] Chen Z C, Zhong C J. Oxidative stress in Alzheimer's disease[J]. Neurosci Bull, 2014,30(2):271-281.[17] Petersen R B, Nunomura A, Lee H G,et al. Signal transduction cascades associated with oxidative stress in Alzheimers disease[J]. J Alzheimers Dis, 2007,11(2):143-152.[18] Tillement L, Lecanu L, Papadopoulos V. Alzheimer's disease: effects of beta-amyloid on mitochondria[J]. Mitochondrion, 2011,11(1):13-21.[19] Snyder E M, Nong Y, Almeida C G, et al. Regulation of NMDA receptor trafficking by amyloid-beta[J]. Nat Neurosci, 2005,8(8):1051-1058.[20] 张旭,王蓉.罗格列酮与阿尔茨海默病[J].首都医科大学学报,2011,32(1):95-99.[21] 亓珅,杜怡峰.炎性反应在阿尔茨海默病发病机制中作用的研究进展[J].中国神经免疫学和神经病学杂志,2013,20(4):278-280,284.[22] Michelucci A, Heurtaux T, Grandbarbe L, et al. Characterization of the microglial phenotype under specific pro-inflammatory and anti-inflammatory conditions: Effects of oligomeric and fibrillar amyloid-β[J]. J Neuroimmunol, 2009,210(1-2):3-12.[23] McGeer E G, McGeer P L. Neuroinflammation in Alzheimer's disease and mild cognitive impairment: a field in its infancy[J]. J Alzheimers Dis, 2010,19(1):355-361.[24] McGeer P L, Rogers J, McGeer E G. Inflammation, anti-inflammatory agents and Alzheimer disease: the last 12 years[J]. J Alzheimers Dis, 2006,9(3 Suppl):271-276.[25] Kyrkanides S, Tallents R H, Miller J N, et al. Osteoarthritis accelerates and exacerbates Alzheimer's disease pathology in mice[J]. J Neuroinflammation, 2011,8:112.[26] 张景燕,王蓉,赵静姝,等.APP5肽类似P165和罗格列酮对SH-SY5Y细胞IRS-1和p-CREB表达的影响[J].首都医科大学学报,2011,32(4):484-488.[27] 张龙,王春梅.胰岛素及其受体和信号传导通路与阿尔兹海默病的研究进展[J].广东医学院学报,2013,31(1):75-77.[28] de la Monte S M, Wands J R. Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system[J]. J Alzheimers Dis, 2005,7(1):45-61.[29] 白莹莹,贾建平.阿尔茨海默病分子遗传学研究进展[J].首都医科大学学报,2010,31(2):177-182. |
