关键词: SYNTAX评分, SYNTAX评分II, 急性ST段抬高型心肌梗死, 经皮冠状动脉介入治疗, 预测

Abstract: Objective To assess the value of SYNTAX score and SYNTAX Ⅱ score to predict no-reflow of primary percutaneous coronary intervention (pPCI) in patients with acute ST-segment elevation myocardial infarction (STEMI). Methods A total of 384 STEMI patients who were diagnosed by coronary angiography within 12 hours were enrolled in the Emergency Critical Care Center of Beijing Anzhen Hospital from January 2016 to January 2017 in this study. No-reflow group (76 cases) and normal blood flow group (308 cases) are divided by reflux phenomenon. SYNTAX score and SYNTAX Ⅱ score were calculated,and the clinical features and laboratory data were collected to compare the differences between groups. Logistics regression analysis was assessed of no-reflow factors,and receiver operating characteristic (ROC) curve analysis was compared the SYNTAX score with SYNTAX Ⅱ score in predictive value of no-reflow phenomenon in STEMI patients. Results Through univariate analysis,SYNTAX score and SYNTAX Ⅱ score were all correlated with no reflow of coronary arteries,but only SYNTAX Ⅱ score was correlated with no reflow of coronary arteries in multivariate analysis. With high SYNTAX Ⅱ score,the risk of coronary non-reflow increased. ROC curve analysis showed that the area under curve of SYNTAX score Ⅱ was larger than SYNTAX score,and the difference was statistically significant (0.905 vs 0.818,P<0.001). Furthermore,the sensitivity and specificity of predicting no reflow were higher than SYNTAX score. Conclusion The SYNTAX Ⅱ score was an independent risk factor of no-reflow and had a better predictive value of no-reflow than the SYNTAX score in STEMI patients.

Key words: SYNTAX score, SYNTAX score II, acute ST-segment elevation myocardial infarction, percutaneous coronary intervention, predictive value