冠状动脉斑块旋磨联合药物洗脱支架术对不同年龄段老年钙化治疗效果的对比分析

doi:10.3969/j.issn.1006-7795.2021.01.017

首都医科大学学报 ›› 2021, Vol. 42 ›› Issue (1): 101-104.doi: 10.3969/j.issn.1006-7795.2021.01.017

冠状动脉斑块旋磨联合药物洗脱支架术对不同年龄段老年钙化治疗效果的对比分析

胡宾, 周玉杰^*, 贾德安, 秦政, 许晓晗, 杨士伟, 周志明

首都医科大学附属北京安贞医院心内科北京市心肺血管疾病研究所冠心病精准治疗北京市重点实验室首都医科大学冠心病临床诊疗与研究中心,北京 100029

收稿日期:2020-04-09 出版日期:2021-02-21 发布日期:2021-02-02
基金资助:
国家重点研发计划(2017YFC0908800),北京市医院管理局“登峰”计划专项经费资助(DFL20150601),北京市医院管理局“使命”计划专项经费资助(SML20180601),北京市卫生健康委员会科技创新中心建设项目(PXM2019_026272_000006,PXM2019_026272_000005)。

Observation on effect of rotational atherectomy followed by drug-eluting stents implantation in patients age ≥65 years with severe calcified coronary lesions

Hu Bin, Zhou Yujie^*, Jia Dean, Qin Zheng, Xu Xiaohan, Yang Shiwei, Zhou Zhimin

Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Disease, Beijing Key Laboratory of Precision Medicine of Coronary Atherosclerotic Disease, Clinical Center for Coronary Heart Disease, Capital Medical University, Beijing 100029, China

Received:2020-04-09 Online:2021-02-21 Published:2021-02-02
Contact: ^*E-mail:azzyj12@163.com
Supported by:
National Key Research and Development Program of China (2017YFC0908800),Beijing Municipal Administration of Hospitals’and Ascent Plan (DFL20150601), Beijing Municipal Administration of Hospitals’ Mission Plan (SML20180601),Beijing Municipal Health Commission “Project of Science and Technology Innovation Center”(PXM2019_026272_000006,PXM2019_026272_000005).

摘要/Abstract

摘要： 目的探讨冠状动脉粥样硬化性心脏病(以下简称冠心病)严重钙化患者的年龄对冠状动脉旋磨联合药物洗脱支架治疗效果及其安全性的影响。方法选取2016年1月至2017年12月连续在首都医科大学附属北京安贞医院接受冠状动脉内旋磨和药物洗脱支架植入治疗的198例冠心病患者为研究对象,分为≥65岁组116例和<65岁组82例,比较两组旋磨治疗的基线特征、并发症、1年主要不良心血管事件,包括因心肌梗死、再次血运重建及死亡。结果 ≥65岁组和<65岁组围术期合并症的发生率分别为18.9％、13.3％,差异无统计学意义 (P=0.202)。两组患者1年主要不良心血管事件比较,差异无统计学意义(P=0.320)。结论冠状动脉内旋磨和药物洗脱支架治疗老年冠心病严重钙化的效果及安全性,不受患者的年龄影响。

关键词: 旋磨术, 药物洗脱支架, 冠状动脉粥样硬化性心脏病

Abstract: Objective To assess the effect of coronary rotational atherectomy followed by drug-eluting stents implantation in patients age ≥65 years with complex calcified coronary lesions. Methods A total of 198 consecutive patients with coronary artery disease receiving rotational atherectomy from January 2016 to December 2017 were retrospectively analyzed.Patients were divided into an ≥65 years group(n=116) and a <65 years group (n=82). We compared the characteristics of rotational atherectomy, peri-procedural complications and 1-year major adverse cardiac events (MACE), comprised of cardiac death, miocardial infarction, target vessel revascularization. Results The incidence of peri-procedural complications had no significant difference between the≥65 years group and the<65 years group(18.9％ vs 13.3％, P=0.202).And the rate of MACE was similar in the ≥65 years and <65 years groups (10.3% vs 7.3％, P=0.320). Conclusion Coronary rotational atherectomy followed by drug-eluting stents implantation is a safe and effective treatment strategy in patients age ≥65 years with complex calcified coronary lesions.

Key words: rotational atherectomy, drug-eluting stents, coronary artery disease

中图分类号:

R541.14

胡宾, 周玉杰, 贾德安, 秦政, 许晓晗, 杨士伟, 周志明. 冠状动脉斑块旋磨联合药物洗脱支架术对不同年龄段老年钙化治疗效果的对比分析[J]. 首都医科大学学报, 2021, 42(1): 101-104.

Hu Bin, Zhou Yujie, Jia Dean, Qin Zheng, Xu Xiaohan, Yang Shiwei, Zhou Zhimin. Observation on effect of rotational atherectomy followed by drug-eluting stents implantation in patients age ≥65 years with severe calcified coronary lesions[J]. Journal of Capital Medical University, 2021, 42(1): 101-104.

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冠状动脉斑块旋磨联合药物洗脱支架术对不同年龄段老年钙化治疗效果的对比分析

Observation on effect of rotational atherectomy followed by drug-eluting stents implantation in patients age ≥65 years with severe calcified coronary lesions

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