Journal of Capital Medical University ›› 2017, Vol. 38 ›› Issue (1): 126-142.doi: 10.3969/j.issn.1006-7795.2017.01.026

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Structure and feature of nano-medicines assembled by biodegradable polymers

Zhao Ming, Peng Shiqi   

  1. School of Pharmaceutical Sciences, Capital Medical University, Beijing 100069, China
  • Received:2017-01-04 Online:2017-01-21 Published:2017-01-20
  • Supported by:
    This study was supported by National Natural Science Foundation of China (81273379, 81373264,81673303), Key Project of Beijing Education Commission (Z141100002114049,KZ201610025029),Beijing Area Major Laboratory of Peptide And Small Molecular Drugs(130011601603).

Abstract: Major progress in the understanding of the onset and pathology of a series of diseases highlights the biodegradable polymers based nano-medicine having desirable pharmaceutical and pharmacological property, targeting disease site, crossing biological barriers, exhibiting multiple functions and monitoring real-time drug-distribution. These advantages of nano-medicines attract a great deal of research interests, and the polymeric biodegradable conjugates have been deeply emphasized by medicinal chemistry in particular. In this regard, the present review focuses on the assembling process and feature of biodegradable polymers based nano-medicines. To get insight into the assembling process of the biodegradable polymers and to visualize the feature of the formed nano-species we provided a number of figures.

Key words: biodegradable polymers, nano-medicine, nano-structure, assembly process, assembly mechanism

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