Analysis of relationship between primary hyperparathyroidism and thyroid diseases

doi:10.3969/j.issn.1006-7795.2017.03.022

Abstract

Abstract: Objective In order to investigate the occurrence of thyroid diseases in primary hyperparathyroidism (PHPT), and analyze the relationship between them. Methods We collected 84 admission cases which were diagnosed as PHPT from 2010 to 2014 in Beijing Shijitan Hospital of the Capital Medical University. Then we analyzed the morbidity of concomitant thyroid diseases and thyroid function. Results Totally 84 cases were diagnosed as PHPT both by surgical and pathological diagnosis. The largest thyroid disease was nodular goiter (62/74),which included 25 single thyroid nodule (33.8%),37 multiple thyroid nodules (50.0%). Besides, 12 cases accompanied medullary thyroid carcinoma (16.2%). Patients with PHPT had low level of total tetraiodothyronine (TT4) and free tetraiodothyronine (FT4)(P<0.05). TT4 and FT4 negatively correlated with serum parathyroid hormone (PTH) (P<0.05). Conclusion Concomitant thyroid diseases in patients with PHPT are arresting. Patients with PHPT have low level of TT4 and FT4, which may be closely related to PTH. We recommend the routine use of ultrasound in patients with PHPT to detect any concomitant thyroid diseases and thus determine the best surgical strategy.

Key words: primary hyperparathyroidism(PTH), thyroid nodule, medullary thyroid carcinoma(MTC), parathyroid hormone(PTH)

CLC Number:

Xiu Lei, Jiang Tao, Fu Yueyue. Analysis of relationship between primary hyperparathyroidism and thyroid diseases[J]. Journal of Capital Medical University, 2017, 38(3): 446-450.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2017.03.022

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2017/V38/I3/446

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