Journal of Capital Medical University ›› 2018, Vol. 39 ›› Issue (6): 945-949.doi: 10.3969/j.issn.1006-7795.2018.06.026

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Analysis of clinical features and cross-sectional echocardiography of lone atrial fibrillation and non-lone atrial fibrillation patients

Cheng Liting, Gao Jiale, Yuan Linhao, Wu Yongquan   

  1. Cardiovascular Center, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
  • Received:2018-04-12 Online:2018-11-21 Published:2018-12-19

Abstract: Objective To explore the clinical features and transthoracic echocardiography results between lone atrial fibrillation and non-lone atrial fibrillation. Methods A total of 159 patients under 60 years old with atrial fibrillation who were admitted to Beijing Friendship Hospital,Capital Medical University from January 2016 to January 2018 were retrospectively collected. According to the existence of cardiopulmonary disease, hypertension, diabetes mellitus etc or not, patients were divided into lone atrial fibrillation group and non-lone atrial fibrillation group. According to whether male patients has a left atrium larger than 4.0 cm and female patients has a left atrium larger than 3.8 cm, lone atrial fibrillation group was further divided into normal left atrial group and left atrial dilated group to explore the clinical features and transthoracic echocardiography results between lone atrial fibrillation and non-lone atrial fibrillation and analysis the result with binary Logistic regression analysis. Results Lone atrial fibrillation compared with non-lone atrial fibrillation group, there were significant differences in the incidence of stroke, left ventricular ejection fraction, left ventricular end systolic diameter and left anteroposterior diameter (P<0.05), but there was no significant difference in age, sex, and left ventricular end diastolic diameter (P>0.05). Multivariate Logistic regression analysis showed that there was no significant difference in stroke events between the two groups (OR:3.781, 95% CI:0.832-17.179, P=0.085). There were significant differences in age, left ventricular end diastolic diameter and left ventricular end systolic diameter (P<0.05) in left atrial enlargement group and left atrial normal group in patients with lone atrial fibrillation. There were no significant differences in sex, body mass index, smoking history, drinking history, history of cerebral apoplexy, left ventricular ejection fraction, right ventricular diameter, atrial fibrillation duration and ascending aorta diameter (P>0.05). Multivariate Logistic regression analysis showed that the age difference between the two groups was statistically significant (OR:1.176, 95% CI:1.007-1.372, P=0.040). Conclusion Patients with lone atrial fibrillation have a small left atrial diameter and low risk of stroke but there was no significant difference in stroke events after correction. The incidence of male patients with lone atrial fibrillation is relatively high, and left atrial diameter is correlated with the age of the patients there is no significant relationship between left atrial diameter and stroke incidents.

Key words: lone atrial fibrillation, non-lone atrial fibrillation, cross-sectional echocardiography, left atrium

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