Abstract: Objective To evaluate safety and efficacy profiles of intracranial aneurysms treated with endovascular techniques. Methods We searched our characteristics of intracranial aneurysms prospectively maintained database of Beijing Chaoyang Hospital, Capital Medical University and identified 91 patients treated with endovascular treatment between the years 2011 and 2016. The patients' angiographic outcomes, clinical outcomes and perioperative complications were reviewed retrospectively. Cox regression analysis were applied to determine the risk factors for aneurysms recurrence and the predictors for clinical outcomes. Results We studied these patients who included 55 females and 36 males with a mean age of (45.9±11.1) years. There were 58 ruptured intracranial aneurysms. Of them, Hunt-Hess Ⅲ-Ⅴ in 9 patients. In 48 aneurysms, the treatment was attempted with coiling alone. Stent-assisted technique (SAT) was in 15 patients and balloon remodeling technique (BRT) in 18 patients. In the follow-up angiography, recurrences rate was observed in 13.2% of the cases. According to Cox regression analysis, size of aneurysm, neck size and ruptured status were independently associated with increased risk of aneurysm recurrence. Good functional outcome was achieved in 87.9%. High Hunt-Hess grade at admission was independent predictors of poor functional outcome in the multivariate analysis. However, 12 patients had procedure-related complications. Conclusion The endovascular treatment of intracranial aneurysms is feasible and has a good clinical outcome. Size of aneurysm, neck size and ruptured status were independently associated with increased risk of aneurysm recurrence. However, patient with high Hunt-Hess grade aneurysms, morbidity and mortality rates remain high.

Key words: intracranial aneurysms, stent-assisted technique, balloon-remodeling technique, angiographic outcomes, clinical outcomes