Clinical characteristics and treatment of elastofibroma dorsi: experience in 71 cases

doi:10.3969/j.issn.1006-7795.2019.01.025

Abstract

Abstract: Objective To summarize the experience in the diagnosis and treatment of elastofibroma dorsi. Methods Clinical data of 71 cases of pathologically determined elastofibroma dorsi from January 2010 to April 2017 were retrospectively reviewed,including clinical characteristics, radiological examinations and pathological alterations, surgery, postoperative complications. Results Most patients were female(57/71)in this series.All the lesions were located within the muscles in the subscapular region.There were 18 cases with bilateral involvement.Patients complained of pain(19/71) and feeling of foreign body(16/71).One case was associated with numbness of the lateral upper limb, and thirty-five patients were asymptomatic.The size of the masses was between 4 centimeters to 14 centimeters,averaging at(8.46±2.67)centimeters.Accurate diagnosis was made in all the cases before the histological exams solely based on the physical examination and imaging findings. Marginal resection was done for all the cases under local anesthesia or general anesthesia.Seroma,as the major complication, which was resolved by repeated paracentesis.Sixty-five cases were followed-up with ultrasonic.No recurrence was found during the follow-up period(2 months to 85 months,median 23.16 months). Conclusion Elastofibroma dorsi is frequently located between inferior corner of scapula and posterior chest wall. It is a very special type of soft tissue tumors that its diagnosis call usually be made solely on the basis of unique imaging characteristics and physical examination before the histological exam.Surgical marginal excision is the choice of treatment with good short-term and long-term results.

Key words: elastofibroma dorsi, surgical operation, diagnosis, computed tomography(CT)

CLC Number:

R738.6

Liu Meng, Zou Dapeng. Clinical characteristics and treatment of elastofibroma dorsi: experience in 71 cases[J]. Journal of Capital Medical University, 2019, 40(1): 143-147.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2019.01.025

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2019/V40/I1/143

References

[1] Nagano S, Yokouchi M, Setoyama T, et al. Elastofibroma dorsi:surgical indications and complications of a rare soft tissue tumor[J]. Mol Clin Oncol, 2014,2(3):421-424.
[2] Parratt M T R, Donaldson J R, Flanagan A M, et al. Elastofibroma dorsi:management,outcome and review of the literature[J]. J Bone Joint Surg Br, 2010,92(2):262-266.
[3] Giebel G D, Bierhoff E, Vogel J. Elastofibroma and pre-elastofibroma-a biopsy and autopsy study[J]. Eur J Surg Oncol, 1996,22(1):93-96.
[4] Kumaratilake J S, Krishman R, Lomax-Smith J, et al. Elastofibroma:disturbed elastic fibrillogenesis by periosteal-derived cells? An immunoelectron microscopic and in situ hybridization study[J]. Hum Pathol, 1991,22(10):1017-1029.
[5] Hernandez J L, Rodriguez-Parets J O, Valero J M, et al. High resolution genomewide analysis of choromosomal alterations in elastofibroma[J]. Virchows Arch,2010,456(6):681-687.
[6] Nishio J N, Iwasaki H, Ohjimi Y, et al. Gain of Xq detected by comparative genomic hybridization in elastofibroma[J]. Int J Mol Med, 2002,10(3):277-280.
[7] Imanishi A, Imanishi H, Yoshida Y, et al. Upregulation of TGF-β1 and basic FGF in elastofibroma:an immunohistochemical analysis[J]. Med Mol Morphol, 2016,49(2):83-88.
[8] Tasli F, Vardar E, Argon A, et al. Histochemical and immunohistochemical characteristics of elastofibromas[J]. Pol J Pathol, 2014,65(2):120-124.
[9] El Hammoumi M, Qtaibi A, Arsalane A, et al. Elastofibroma dorsi:clinicopathological analysis of 76 cases[J]. Korean J Thorac Cardiovasc Surg,2014,47(2):111-116.
[10] Deveci M A, Ozbarlas H S, Erdogan K E, et al. Elastofibroma dorsi:Clinical evaluation of 61 cases and review of the literature[J]. Acta Orthop Traumatol Turc, 2017, 51(1):7-11.
[11] Alberghini M, Bacchini P, Pignatti G, et al. Histochemical and ultrastructural study of an elastofibroma dorsi coexisting with a high grade spindle cell sarcoma[J].Eur J Histochem,2004,48(2):173-178.
[12] 王昌明,宋世兵,蒋斌,等.背部弹力纤维瘤10例诊治分析[J].中华普通外科杂志,2009,24(10):827-830.
[13] 丁华杰,刘会玲,那磊,等.超声与CT在良恶性软组织肿瘤中的诊断价值[J].中国煤炭工业医学杂志,2016,19(6):847-850.
[14] Cakmak G, Ergun T, Sahin M S, Arthroscopic excision of elastofibroma dorsi at scapulothoracic joint:a surgical technique[J]. Eklem Hastalik Cerrahisi,2014,25(2):117-120[Article in Turkish].
[15] Abat F, Alverez C, Trullols L, et al. Elastofibroma dorsi:a 7-year follow-up of 37 cases and a review of the literature[J]. Rev Esp Cir Ortop Traumatol,2012,56(4):295-300.
[16] Nagamine N, Nohara Y, Ito E. Elastofibroma in Okinawa. A clinicopathologic study of 170 cases[J]. Cancer,1982,50(9):1794-1805.
[17] Lococo F, Cesario A, Mattei F, et al. Elastofibroma dorsi:clinicopathological analysis of 71 cases[J]. Thorac Cardiovasc Surg,2013,61(3):215-222.