Clinical observation of abdominal acupuncture in the treatment of obesity caused by atypical antipsychotics

doi:10.3969/j.issn.1006-7795.2020.01.015

Journal of Capital Medical University ›› 2020, Vol. 41 ›› Issue (1): 75-79.doi: 10.3969/j.issn.1006-7795.2020.01.015

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Clinical observation of abdominal acupuncture in the treatment of obesity caused by atypical antipsychotics

Li Xue^1,2, Zhu Hong^1,2, Fang Meng^1,2, Ning Yanzhe^1,2, Zhao Shuang^1,2, Yin Dongqing^1,2

1. The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing 100088, China;
2. Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing 100069, China

Received:2019-12-01 Online:2020-02-21 Published:2020-02-13
Supported by:
This study was supported by Chinese Medicine Science and Technology Development Found of Beijing (JJ 2018-42,QN2018-26),Capital Health Research and Development of Special Founding(2018-1-2122), Scientific Research and Cultivation Fund of Beijing Hospital Management Center(PZ2019033), Beijing Hospitals Authority' Ascent Plan (DFL20191901).

Abstract

Abstract: Objective To investigate the effects of abdominal acupuncture on body weight, waist circumference, body mass index (BMI), and blood lipids in obese patients with atypical antipsychotics.Methods Sixty patients with obesity caused by atypical antipsychotics were divided into a treatment group (30 cases) and a control group (30 cases). The treatment group was treated with abdominal acupuncture, while the control group with health guidance. The changes of body weight, waist circumference, BMI and blood lipid levels of patients in the two groups before treatment were observed, on the 28th day and on the 56th day.Results Repeated multivariate analysis of variance was used to study the results. The results showed that the time effects and grouping effects on weight, waist circumference, BMI, cholesterol and triglycerides were significantly interactive (P<0.05). Further analysis indicated that the waist circumference and BMI data on the 28th day of treatment were better than the control group (P<0.05). On the 56th day, the weight, waist circumference, BMI, and triglyceride data of the treatment group were better than the control group (P<0.05), with the statistically significant difference. Conclusion Abdominal acupuncture can decrease the body weight, BMI, and lipid metabolism of obese patients with antipsychotics.

Key words: abdominal acupuncture, atypical antipsychotics, obese patients, lipid metabolism

CLC Number:

R749.3

Li Xue, Zhu Hong, Fang Meng, Ning Yanzhe, Zhao Shuang, Yin Dongqing. Clinical observation of abdominal acupuncture in the treatment of obesity caused by atypical antipsychotics[J]. Journal of Capital Medical University, 2020, 41(1): 75-79.

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References

[1] 刘生,王高华,王惠玲.抗精神病药物治疗所致药源性肥胖与2型糖尿病的关系[J].国际精神病学杂志,2008(3):176-179.
[2] Mitchell A J,Vancampfort D,De Herdt A,et al. Is the prevalence of metabolic syndrome and metabolic abnormalities increased in early schizophrenia?A comparative meta-analysis of first episode,untreated and treated patients[J]. Schizophr Bull,2013,39:295-305.
[3] 陈春明,孔灵芝.中国成人超重和肥胖症预防控制指南[M]北京.人民卫生出版社,2006,4.
[4] World Health Organization. The ICD-10 classification of mental and behavioural disorders. Clinical description and diagnostic guideline[M]. Geneva:World Health Organization,1992:8.
[5] Leucht S,Corves C,ArbterD,et al. Second-generation versus first-generation antipsychotic drugs for schizophrenia:a meta-analysis[J].Lancet,2009,373(9657):31-41.
[6] Henderson D C,Cagliero E,Cray C,et al. Clozapine,diabetes mellitus,weight gain,and lipid abnormalities:a five-year naturalistic study[J]. Am J Psychiat,2000,157(6):975-978.
[7] Patel J K,Buckley P F,Woolson S,et al. Metabolic profiles of second-generation antipsychotics in early psychosis:findings from the CAFE study[J]. Schizophr Res,2009,111(1-3):9-16.
[8] Hwang Y J,Dixon S N,Reiss J P,et al. Atypical antipsychotic drugs and the risk for acute kidney injury and other adverse outcomes in older adults:a population-based cohort study[J]. Ann Intern Med,2014,161(4):242-248.
[9] 赵帅,周晓琴,夏海龙,等.住院精神分裂症患者心血管疾病发生风险研究[J].中国神经精神疾病杂志,2017,43(9):539-543.
[10] OLfson M,Gerhard T,Huang C,et al. Premature mortality among adults with schizophrenia in the United States[J]. JAMA Psychiat,2015,72(12):1172-1181.
[11] Nicole E M,Chantel K,Sri M A,et al. Antipsychotics,metabolic adverse effects,and cognitive function in schizophrenia[J]. Front Psychiat,2018,5(9):622.
[12] Raben A T,Marshe V S,Chintoh A,et al. The complex relationship between antipsychotic-induced weight gain and therapeutic benefits:a systematic review and implications for treatment[J]. Front Neurosci,2017,11:741.
[13] Haffner S M. The metabolic syndrome:inflammation,diabetes mellitus,and cardiovascular disease[J]. Am J Cardiol,2006,97(2A):3A-11A.
[14] Chen P Y,Huang M C,Chiu C C,et al. Association of plasma reti-nol-binding protein-4,adiponectin,and high molecular weight adiponectin with metabolic adversities in patients with schizophrenia[J]. Pro Neuropsychopharmacol Bio-Psychiat,2011,35(8):1927-1932.
[15] Bae Y J,Kim S H,Chung J H,et al. Evaluation of adiposity-related biomarkers as metabolic syndrome indicators[J]. Clin Nutr Res, 2013,2:91-99.
[16] 薄智云.腹针疗法[M].北京:中国科学技术出版社,1999:46-67,92-93.
[17] 杨礼泛,黄龙坚,吕艳,等.腹针治疗单纯性肥胖临床疗效Meta分析[J].中医临床研究,2015,7(31):1-4.
[18] 张蕾,丁瑛,张丽娜,等.腹针对奥氮平所致肥胖脂代谢的影响[J].中国针灸,2017,37(6):591-593
[19] 蔡荣林,管媛媛,武红利,等.胃俞募配穴针刺与胃俞、中脘单穴针刺对健康受试者胃扩张状态下静息态脑功能局部一致性的影响[J].中国针灸,2018,38(4):379-385.

Clinical observation of abdominal acupuncture in the treatment of obesity caused by atypical antipsychotics

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