Ang (1-7) improves skeletal muscle lipid metabolism and insulin resistance by regulating endoplasmic reticulum stress

doi:10.3969/j.issn.1006-7795.2018.04.010

Abstract

Abstract: Insulin resistance of skeletal muscle plays an important role in the pathogenesis of type 2 diabetes. Angiotensin can improve skeletal muscle lipid metabolism through endoplasmic reticulum stress and thus improve insulin resistance. In recent years, the specific molecular mechanism of endoplasmic reticulum stress has been explored. This paper mainly discusses the effect of endoplasmic reticulum stress on the lipid metabolism and insulin resistance of skeletal muscle and the possible mechanism.

Key words: angiotensin, endoplasmic reticulum stress, skeletal muscle lipid metabolism, insulin resistance

CLC Number:

R587.1

Lu Xingmeng, Xin Zhong. Ang (1-7) improves skeletal muscle lipid metabolism and insulin resistance by regulating endoplasmic reticulum stress[J]. Journal of Capital Medical University, 2018, 39(4): 532-536.

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URL: https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/10.3969/j.issn.1006-7795.2018.04.010

https://journal03.magtech.org.cn/Jweb_sdykdxxb/EN/Y2018/V39/I4/532

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