Incidence and influence factors of endoscopic non-curative resection of early gastric cancer

doi:10.3969/j.issn.1006-7795.2022.01.004

Journal of Capital Medical University ›› 2022, Vol. 43 ›› Issue (1): 17-21.doi: 10.3969/j.issn.1006-7795.2022.01.004

• Basic and Clinical Research of Gastroenteroloy • Previous Articles Next Articles

Incidence and influence factors of endoscopic non-curative resection of early gastric cancer

Ma Zonghui, Zhang Qian, Xing Jie, Zhu Shengtao, Li Peng, Zhang Shutian, Sun Xiujing^*

Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Diseases, Beijing Digestive Disease Center, Faculty of Gastroenterology of Capital Medical University, Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing 100050, China

Received:2021-11-23 Online:2022-02-21 Published:2022-01-27
Contact: * E-mail:sunxiujing@ccmu.edu.cn
Supported by:
Natural Science Foundation of Beijing (7204249),National Key R&D Program of China(2017YFC1700601),The Digestive Medical Coordinated Development Center of Beijing Hospitals Authority(XXZ01,XXZ02).

Abstract

Abstract: Objective To explore the incidence and influence factors of non-curative resection after endoscopic resection of early gastric cancer. Methods We retrospectively collected the relevant data of patients with early gastric cancer who were hospitalized in the Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University from January 2014 to August 2020, and then we evaluated the resection's curability, calculated the incidence of non-curative resection, and analyzed its influence factors. Results A total of 347 lesions of early gastric cancer were included, of which 66 were non-curative resection lesions, thus the non-curative resection rate was 19.02% (66/347). Multivariate Logistic analysis showed that the lesions with diameter ≥20 mm (OR=3.248, 95%CI: 1.451-7.272, P=0.004), infiltration into submucosa (OR=26.549, 95%CI:10.087-69.875, P<0.001) and the pathological type of undifferentiated early gastric cancer (OR=18.021, 95%CI: 6.664-48.736, P<0.001) were influence independent factors for non-curative resection. Conclusion The endoscopic resection should be applied carefully after full evaluation for early gastric cancer with diameter ≥20 mm and infiltration into submucosa and/or undifferentiated pathological type as suggested by preoperative pathology.

Key words: early gastric cancer, endoscopic resection, non-curative resection

CLC Number:

R735.2

Ma Zonghui, Zhang Qian, Xing Jie, Zhu Shengtao, Li Peng, Zhang Shutian, Sun Xiujing. Incidence and influence factors of endoscopic non-curative resection of early gastric cancer[J]. Journal of Capital Medical University, 2022, 43(1): 17-21.

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Incidence and influence factors of endoscopic non-curative resection of early gastric cancer

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